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Updated: Mar 29, 2026

Midface Hypoplasia and Cranial Base Morphology in Syndromic Craniosynostosis: A Comparative Analysis Study Using a Predictive Regression Model
Published on: November 4, 2025
Prenatal Imaging of Craniosynostosis Syndromes
Pamela Deaver Ketwaroo1, Caroline D Robson1, Judy A Estroff2
1Department of Radiology, Boston Children's Hospital, Harvard Medical School, Boston, MA.
Abstract:
This article reviews the prenatal diagnosis of those syndromes in which craniosynostosis is a key feature. Although not an exhaustive list, the authors highlight conditions that may be encountered with some regularity, especially in a higher volume fetal imaging center. Rare conditions are also discussed. Normal sutural anatomy and development are first reviewed, followed by a discussion of specific syndromes, the salient imaging findings, and pathologic as well as postnatal correlations when possible.
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