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Rotavirus is Predominent Enteropathogen in Acute Childhood Diarrhea in Mymensingh

S R Sarkar1, M A Hossain, S K Paul

  • 1Dr Santana Rani Sarkar, Medical Officer, Department of Microbiology, Mymensingh Medical College (MMC), Mymensingh, Bangladesh.

Mymensingh Medical Journal : MMJ
|December 2, 2015
PubMed

Insights

Rotavirus was the most frequent cause of diarrhea in pediatric patients, followed by Diarrheagenic Escherichia coli (DEC). These findings highlight key pathogens in pediatric diarrheal disease surveillance.

Area of Science:

  • Medical Microbiology
  • Pediatric Infectious Diseases

Background:

  • Diarrheal diseases pose a significant health burden in pediatric populations worldwide.
  • Accurate identification of enteropathogens is crucial for effective treatment and public health strategies.

Purpose of the Study:

  • To identify common enteropathogens causing diarrhea in pediatric patients.
  • To determine the prevalence of specific pathogens like Rotavirus and Diarrheagenic Escherichia coli (DEC).

Main Methods:

  • Stool specimens from 200 pediatric patients with diarrhea were analyzed.
  • Standard laboratory methods were used for pathogen identification.
  • Multiplex PCR detected Diarrheagenic Escherichia coli (DEC); Polyacrylamide Gel Electrophoresis (PAGE) detected Rotavirus.

Main Results:

  • Rotavirus was the most prevalent enteropathogen, identified in 34.5% of cases.
  • Diarrheagenic Escherichia coli (DEC) was detected in 17.0% of cases.
  • Campylobacter species were found in 11.5% of cases, with Rotavirus being most common in infants under 1 year old.

Conclusions:

  • Rotavirus is a leading cause of pediatric diarrhea in the studied population.
  • DEC and Campylobacter are also significant contributors to pediatric diarrheal illness.
  • Findings support the importance of surveillance for these enteropathogens in pediatric care.

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