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Drug therapies to delay the progression of chronic kidney disease

Frank Ward1, John Holian1, Patrick T Murray2

  • 1St Vincent's University Hospital, Dublin 4, Ireland.

Clinical Medicine (London, England)
|December 2, 2015
PubMed

Insights

Chronic kidney disease (CKD) is a growing global health issue. This review explores treatments to slow CKD progression and reduce associated cardiovascular risks.

Area of Science:

  • Nephrology
  • Cardiovascular Medicine
  • Pharmacology

Background:

  • Chronic kidney disease (CKD) presents a significant global health burden, marked by high rates of cardiovascular complications and mortality.
  • Despite advances, CKD incidence is rising worldwide, termed a 'silent epidemic'.
  • Managing advanced CKD incurs substantial patient and economic costs.

Purpose of the Study:

  • To review established and novel therapeutic agents for delaying CKD progression.
  • To identify interventions that can improve patient outcomes in CKD.

Main Methods:

  • Literature review of established and emerging pharmacological agents.
  • Analysis of studies focusing on delaying CKD progression and cardiovascular events.

Main Results:

  • The review synthesizes current knowledge on therapeutic strategies.
  • Identifies agents with potential to mitigate CKD advancement and associated risks.

Conclusions:

  • Effective interventions are crucial to combat the rising tide of CKD.
  • Further research into novel agents may offer improved patient outcomes and reduced healthcare burdens.

Keywords:
Chronic kidney diseasedrug therapyprogression

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