Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Attention-Deficit/Hyperactivity Disorder01:30

Attention-Deficit/Hyperactivity Disorder

1.3K
Attention-deficit/hyperactivity disorder (ADHD) is a neurodevelopmental disorder characterized by persistent inattention, hyperactivity, and impulsivity. It affects approximately 5-8% of children globally, with around 60-70% of cases persisting into adulthood. ADHD has significant implications for educational attainment, social interactions, and occupational success.
Diagnostic Criteria and Symptoms
To diagnose ADHD, symptoms must manifest before age 12 and be evident across multiple settings....
1.3K
Insulin: Dosing Regimen and Adverse Effects01:16

Insulin: Dosing Regimen and Adverse Effects

1.2K
Insulin-replacement therapy usually includes both long-acting insulin (basal) and short-acting insulin (to cater to postprandial needs). In a diverse group of type 1 diabetes patients, the average daily insulin dose is typically 0.5-0.7 units/kg body weight. However, obese patients and pubertal adolescents may need more due to insulin resistance.
The basal dose constitutes about 40%-50% of the total daily dose, with the rest as premeal insulin. The mealtime insulin dose should mirror...
1.2K
Diabetes Mellitus: Overview and Type I Subtype01:22

Diabetes Mellitus: Overview and Type I Subtype

6.0K
Diabetes mellitus is a chronic metabolic disorder characterized by high blood glucose levels due to inadequate insulin production, insulin resistance, or both. The condition affects millions worldwide and can significantly impact their health and quality of life.
Type 1 diabetes is an autoimmune disease in which the immune system mistakenly attacks and destroys the insulin-producing beta cells in the pancreas. As a result, the body is unable to produce sufficient insulin, and individuals with...
6.0K
Insulin: The Receptor and Signaling Pathways01:28

Insulin: The Receptor and Signaling Pathways

6.0K
Insulin action is mediated through a receptor tyrosine kinase, akin to the IGF-1 receptor. The number of receptors per cell varies significantly, from 40 on erythrocytes to 300,000 on adipocytes and hepatocytes. The insulin receptor consists of linked α/β subunit dimers, forming a heterotetramer glycoprotein with two extracellular α subunits and two β subunits spanning the membrane. The α subunits inhibit the inherent tyrosine kinase activity of the β subunits, but...
6.0K
Self-Regulation01:25

Self-Regulation

322
Self-regulation, also known as self-control, encompasses a range of cognitive and behavioral processes that allow individuals to adjust their internal states and outward actions to align with socially acceptable norms and long-term goals. It plays a fundamental role in adaptive functioning, from resisting impulsive behaviors to persisting through challenging tasks. While its benefits are widely recognized, self-regulation is not limitless. Muraven and Baumeister's theory posits that...
322
Diabetes: Symptoms, Diagnosis, and Complications01:15

Diabetes: Symptoms, Diagnosis, and Complications

2.8K
For most patients, experiencing several weeks of polyuria, polydipsia, fatigue, and significant weight loss may indicate the presence of diabetes. Furthermore, adults displaying the phenotypic appearance of type 2 diabetes (particularly those who are obese and not initially insulin-requiring), may have islet cell autoantibodies, suggesting autoimmune-mediated β cell destruction and a diagnosis of latent autoimmune diabetes of adults (LADA). The categorization of glucose homeostasis is...
2.8K

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Polarization-State-Dependent Charge Screening in Metal-Ferroelectric-Metal Memcapacitors Enabled by an IGZO Oxygen Reservoir Layer.

ACS applied materials & interfaces·2026
Same author

All-Oxide ITO/HZO/WO<sub><i>x</i></sub> Ferroelectric Tunnel Junctions with Oxygen-Engineered Interfaces for Highly Endurable Neuromorphic Computing.

ACS applied materials & interfaces·2026
Same author

Asymmetric Polarization in FE/AFE Bilayer HZO Memcapacitors via Composition-Induced Built-in Bias.

ACS applied materials & interfaces·2026
Same author

Health impacts of a short-lived, small-scale wildfire in South Korea.

International journal of epidemiology·2026
Same author

Low-Voltage and High-k Properties of Bilayer HZO Capacitors at the Morphotropic Phase Boundary for Next-Generation Memory Applications.

Advanced science (Weinheim, Baden-Wurttemberg, Germany)·2026
Same author

K-MIMIC: a nationwide Korean multi-institutional Multimodal intensive care dataset.

Korean journal of anesthesiology·2026

Related Experiment Video

Updated: Mar 29, 2026

Disruption of Frontal Lobe Neural Synchrony During Cognitive Control by Alcohol Intoxication
09:26

Disruption of Frontal Lobe Neural Synchrony During Cognitive Control by Alcohol Intoxication

Published on: February 6, 2019

22.4K

Association between insulin and executive functioning in alcohol dependence: a pilot study.

Changwoo Han1, Hwallip Bae2, Sung-Doo Won3

  • 1Department of Psychiatry, Ansan Hospital, College of Medicine, Korea University, Ansan, Republic of Korea.

Neuropsychiatric Disease and Treatment
|December 2, 2015
PubMed
Summary

This study found that insulin levels are linked to cognitive function in individuals with alcohol dependence. Lower insulin may indicate poorer executive functioning, suggesting insulin as a potential biomarker for cognitive health in this population.

Keywords:
alcohol dependenceexecutive functioninsulintrail making test

More Related Videos

Chronic Intermittent Ethanol Vapor Exposure Paired with Two-Bottle Choice to Model Alcohol Use Disorder
05:12

Chronic Intermittent Ethanol Vapor Exposure Paired with Two-Bottle Choice to Model Alcohol Use Disorder

Published on: June 23, 2023

1.7K
The Motivation for Alcohol Reward: Predictors of Progressive-Ratio Intravenous Alcohol Self-Administration in Humans
05:40

The Motivation for Alcohol Reward: Predictors of Progressive-Ratio Intravenous Alcohol Self-Administration in Humans

Published on: April 28, 2022

3.8K

Related Experiment Videos

Last Updated: Mar 29, 2026

Disruption of Frontal Lobe Neural Synchrony During Cognitive Control by Alcohol Intoxication
09:26

Disruption of Frontal Lobe Neural Synchrony During Cognitive Control by Alcohol Intoxication

Published on: February 6, 2019

22.4K
Chronic Intermittent Ethanol Vapor Exposure Paired with Two-Bottle Choice to Model Alcohol Use Disorder
05:12

Chronic Intermittent Ethanol Vapor Exposure Paired with Two-Bottle Choice to Model Alcohol Use Disorder

Published on: June 23, 2023

1.7K
The Motivation for Alcohol Reward: Predictors of Progressive-Ratio Intravenous Alcohol Self-Administration in Humans
05:40

The Motivation for Alcohol Reward: Predictors of Progressive-Ratio Intravenous Alcohol Self-Administration in Humans

Published on: April 28, 2022

3.8K

Area of Science:

  • Neuroscience
  • Endocrinology
  • Psychiatry

Background:

  • Alcohol dependence is a complex disorder associated with cognitive impairment.
  • Insulin dysregulation, common in diabetes, can also cause cognitive deficits.
  • Patients with alcohol dependence may be at increased risk for insulin dysregulation.

Purpose of the Study:

  • To examine the relationship between cognitive functioning and insulin levels in alcohol-dependent patients.
  • To investigate the potential of insulin as a biomarker for cognitive function in this population.

Main Methods:

  • Assessed cognitive functions using the Korean version of the Consortium to Establish a Registry for Alzheimer's Disease (CERAD-K) in 45 chronic alcoholism patients.
  • Measured serum insulin levels in the study participants.
  • Analyzed correlations between serum insulin levels and various cognitive function scores.

Main Results:

  • Serum insulin levels showed no significant correlation with most CERAD-K cognitive scores.
  • A significant negative correlation was observed between serum insulin levels and the Trail Making Test B (executive functioning).
  • Lower insulin levels were associated with slower executive functioning, indicating a potential direct relationship.

Conclusions:

  • Insulin levels are associated with cognitive functioning in patients with alcohol dependence.
  • Serum insulin may serve as a potential biomarker for assessing cognitive function in individuals with chronic alcoholism.