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Simplified Reverse Genetics Method to Recover Recombinant Rotaviruses Expressing Reporter Proteins
Published on: April 17, 2020
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Ovine rotaviruses
1Division of Veterinary Microbiology and Immunology, Faculty of Veterinary Sciences and Animal Husbandry, R.S.Pura, SKUAST-Jammu-181102, India.
Open Veterinary Journal
|December 2, 2015
Summary
Ovine rotavirus, a cause of diarrhea in young animals and humans, remains poorly understood. Recent studies identified circulating G and P types, with strain NT showing vaccine potential for infants.
Area of Science:
- Veterinary Virology
- Molecular Biology
- Public Health
Background:
- Rotavirus is a major cause of acute diarrhea in young animals and humans.
- Ovine rotavirus strains are classified into serogroups A and B.
- Limited data exists on ovine rotavirus strains globally.
Purpose of the Study:
- To summarize current knowledge on ovine rotavirus.
- To highlight recent findings on circulating G and P types in ovine populations.
- To discuss the potential of ovine rotavirus strain NT as a vaccine candidate.
Main Methods:
- Review of existing literature on ovine rotavirus.
- Analysis of G and P typing data for circulating ovine strains.
- Evaluation of ovine rotavirus strain NT for vaccine potential.
Main Results:
- Ovine rotaviruses are primarily classified into serogroups A and B.
- Recent identification of circulating G and P types in ovine rotaviruses.
- Ovine rotavirus strain NT, isolated from a diarrheic lamb, shows promise as a human infant vaccine candidate.
Conclusions:
- Further characterization of ovine rotavirus strains is needed.
- Understanding circulating G and P types is crucial for control strategies.
- Ovine rotavirus strain NT represents a potential breakthrough for rotavirus vaccination in infants.
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