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Related Concept Videos

Mass Analyzers: Common Types01:19

Mass Analyzers: Common Types

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The quadrupole mass analyzer consists of four cylindrical metal rods arranged in a diamond carrying a DC voltage and a radio-frequency AC voltage. The motion of ions through the quadrupole depends on the field strength, causing only ions of a certain m/z to resonate successfully and strike the detector at a given field strength. Though the transmission rate for these analyzers is high, the exact elemental composition of the sample is not determined because of low resolution; however, they are...
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Tandem mass spectrometry is a technique that uses multiple mass analyzers in series to obtain a higher selectivity and reduce chemical noise during analyte detection. Instruments with multiple analyzers separated by an interaction cell enable secondary fragmentation and selected study of the fragment ions.Secondary fragmentations occur in the interaction cell and can be induced by various factors. Fragmentation induced by collision with inert gases, such as N2, Ar, He, etc., is called...
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Inductively Coupled Plasma Atomic Emission Spectroscopy: Instrumentation01:26

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Inductively coupled plasma (ICP) is the common plasma source used in atomic emission spectroscopy (AES), a technique that detects and analyzes various elements in a sample. This method is often called inductively coupled plasma atomic emission spectroscopy (ICP-AES).
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Inductively Coupled Plasma–Mass Spectrometry (ICP–MS): Overview01:19

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In inductively coupled plasma–mass spectrometry (ICP–MS), an inductively coupled plasma (ICP) torch is used as an atomizer and ionizer. Solid samples are dissolved and volatilized before being introduced into the high-temperature argon plasma, while solution samples are nebulized and passed through the high-temperature argon plasma. Plasma dissociates the analytes and ionizes their component atoms to form a mixture of positive ions and molecular species. The positive ions are then...
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The mass analyzer is a crucial component of the mass spectrometer. In the ionization chamber, the vaporized sample is bombarded with a high-energy electron beam to generate a radical cation and further fragment into neutral molecules, radicals, and cations. A series of negatively charged accelerator plates accelerate the cations into the mass analyzer. The mass analyzer separates ions according to their mass-to-charge (m/z) ratios and then directs them to the detector. The common types of mass...
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Spectrally reconfigurable integrated multi-spot particle trap.

Kaelyn D Leake, Michael A B Olson, Damla Ozcelik

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    Researchers developed a reconfigurable optical particle trap on a chip. By changing light wavelength, they control multiple trapping spots for precise particle manipulation in biophotonic assays.

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    Area of Science:

    • Optofluidics
    • Photonics
    • Biophysics

    Background:

    • Optical manipulation techniques are crucial in various scientific fields.
    • Integrating particle manipulation with optofluidic chips is an emerging area of research.

    Purpose of the Study:

    • To develop a novel, reconfigurable, integrated optical particle trap.
    • To leverage wavelength dependence for dynamic control of trapping spots.

    Main Methods:

    • Utilized multimode interference (MMI) waveguides for multi-spot pattern formation.
    • Employed wavelength control to dynamically alter the number of trapping spots.
    • Integrated optical trapping with a fluidic channel on a chip.

    Main Results:

    • Demonstrated a new type of reconfigurable optical particle trap.
    • Showcased dynamic control over the number of trapping spots by altering wavelength.
    • Achieved deterministic movement of single and multiple particles between trapping locations.

    Conclusions:

    • The developed spectral reconfigurable trap offers precise control over particle manipulation.
    • This integrated multi-particle trap can serve as a foundation for high-throughput biophotonic assays.
    • The technology holds promise for advancing lab-on-a-chip applications.