Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Molecular-Extrusion-Driven Halogen Homogenization for Efficient Perovskite-Silicon Tandem Solar Cells.

Angewandte Chemie (International ed. in English)·2026
Same author

Icariin alleviates ovariectomy-induced osteoporosis by promoting M2 macrophage polarization and suppressing osteoclast activation.

Cytokine·2026
Same author

An Integrated Study Based on UPLC-QTOF/MS Network Pharmacology and In Vivo Validation of the Anti-Obesity Effects of the 60% Ethanol-Eluted Fraction from <i>Rheum tanguticum</i>.

Plants (Basel, Switzerland)·2026
Same author

A Comprehensive Strategy for Characterizing Metabolites and Metabolic Profile in Rat Urine and Feces Following Oral Administration of Huachansu Tablets Based on UPLC-ESI-QTOF/MS<sup>E</sup>.

Biomedical chromatography : BMC·2026
Same author

Anterior Quadratus Lumborum Block with Liposomal Bupivacaine versus Ropivacaine for Postoperative Recovery in Laparoscopic Colorectal Surgery: A Randomized Controlled Trial.

Drug design, development and therapy·2026
Same author

Sponge-like porous Pd-SnO<sub>2</sub> with atomic-level doping for ultrafast and stable CO detection: Synergistic effects of lattice distortion and oxygen vacancies.

Talanta·2026

Related Experiment Video

Updated: Mar 29, 2026

Author Spotlight: Optimizing EAS with Long Electrodes for Enhanced Cochlear Coverage and Hearing Preservation
03:49

Author Spotlight: Optimizing EAS with Long Electrodes for Enhanced Cochlear Coverage and Hearing Preservation

Published on: October 11, 2024

1.3K

Direct Intracochlear Acoustic Stimulation Using a PZT Microactuator.

Chuan Luo1, Irina Omelchenko2, Robert Manson3

  • 1Department of Mechanical Engineering, University of Washington, Seattle, WA, USA Department of Precision Instruments, Tsinghua University, Beijing, China.

Trends in Hearing
|December 4, 2015
PubMed
Summary
This summary is machine-generated.

A novel acoustic microactuator delivers sound directly to the cochlea, showing promise for enhanced hearing solutions. This device achieved auditory brainstem responses comparable to traditional methods in a guinea pig model.

Keywords:
Cochlear implantPZTcochleaelectroacoustichearing aidhybridperilymphpiezoelectric

More Related Videos

Optogenetic Stimulation of the Auditory Nerve
10:53

Optogenetic Stimulation of the Auditory Nerve

Published on: October 8, 2014

15.2K
The Miniature Pig: A Large Animal Model for Cochlear Implant Research
06:16

The Miniature Pig: A Large Animal Model for Cochlear Implant Research

Published on: July 28, 2022

3.8K

Related Experiment Videos

Last Updated: Mar 29, 2026

Author Spotlight: Optimizing EAS with Long Electrodes for Enhanced Cochlear Coverage and Hearing Preservation
03:49

Author Spotlight: Optimizing EAS with Long Electrodes for Enhanced Cochlear Coverage and Hearing Preservation

Published on: October 11, 2024

1.3K
Optogenetic Stimulation of the Auditory Nerve
10:53

Optogenetic Stimulation of the Auditory Nerve

Published on: October 8, 2014

15.2K
The Miniature Pig: A Large Animal Model for Cochlear Implant Research
06:16

The Miniature Pig: A Large Animal Model for Cochlear Implant Research

Published on: July 28, 2022

3.8K

Area of Science:

  • Biomedical Engineering
  • Neuroscience
  • Otolaryngology

Background:

  • Combined electric and acoustic stimulation can improve hearing for some cochlear implant users.
  • Directly delivering acoustic stimuli to the cochlea's scala tympani is a potential therapeutic strategy.

Purpose of the Study:

  • To describe and evaluate a novel acoustic microactuator for in vivo cochlear stimulation.
  • To assess the actuator's ability to elicit auditory brainstem responses (ABRs) in a guinea pig model.

Main Methods:

  • An 800 µm acoustic microactuator with a piezoelectric thin film was implanted in the guinea pig cochlea via the round window.
  • Auditory brainstem response (ABR) thresholds, latencies, and amplitude growth were measured for the actuator and an ear canal speaker.
  • Histologic analysis was performed to assess cochlear damage.

Main Results:

  • The microactuator successfully elicited ABRs in vivo.
  • Stimulation via the microactuator demonstrated latencies and amplitude growth functions comparable to ear canal stimulation.
  • No significant hearing loss was observed post-procedure, and cochlear histology showed minimal damage.

Conclusions:

  • The developed acoustic microactuator is capable of in vivo cochlear stimulation, producing auditory responses similar to conventional methods.
  • This device holds potential for integration into bimodal hearing devices and cochlear implants.
  • Further research is needed to evaluate long-term safety and efficacy.