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Letting Go of JuNK by Disassembly of Adhesive Complexes
Jonathan E Farley1, Marc R Freeman1
1Department of Neurobiology/HHMI, University of Massachusetts Medical School, Worcester, MA 01605, USA.
Neuron
|December 6, 2015
Abstract:
Immature neural circuits form excessive synaptic connections that are later refined through pruning of exuberant branches. In this issue, Bornstein et al. identify a role for JNK signaling in selective axon elimination through disassembly of cell adhesion complexes.
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