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A Research Method For Detecting Transient Myocardial Ischemia In Patients With Suspected Acute Coronary Syndrome Using Continuous ST-segment Analysis
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Fragmented QRS complexes have predictive value of imperfect ST-segment resolution in patients with STEMI after

Xianghong Ma1, Wenting Duan1, Pradeep Poudel2

  • 1Cardiovascular Institute, Second Hospital of Tianjin Medical University, Tianjin, China, 300211.

The American Journal of Emergency Medicine
|December 9, 2015
PubMed

Insights

Fragmented QRS complexes (fQRS) in ST-elevation myocardial infarction patients undergoing primary percutaneous coronary intervention (p-PCI) predict worse outcomes. fQRS identifies patients with severe coronary lesions and impaired left ventricular function.

Area of Science:

  • Cardiology
  • Electrophysiology

Background:

  • Fragmented QRS complexes (fQRS) are associated with various cardiac conditions.
  • Their predictive value in ST-elevation myocardial infarction (STEMI) patients undergoing primary percutaneous coronary intervention (p-PCI) requires further investigation.

Purpose of the Study:

  • To investigate the clinical characteristics of STEMI patients with fQRS.
  • To determine the predictive value of fQRS for outcomes after p-PCI.

Main Methods:

  • The study included 227 STEMI patients undergoing p-PCI.
  • Clinical data, ECG parameters, and coronary angiography results were analyzed.
  • The relationship between fQRS and ST-segment resolution post-PCI was assessed.

Main Results:

  • Patients with fQRS exhibited higher troponin I, creatine kinase-MB levels, prolonged QRS duration, higher Gensini scores, and lower ST-segment resolution and left ventricular ejection fraction.
  • Gensini score and ST-segment resolution were independently associated with fQRS.
  • fQRS presence and number of leads with fQRS were independent predictors of imperfect ST-segment resolution.

Conclusions:

  • fQRS is a valuable predictor in STEMI patients undergoing p-PCI.
  • fQRS aids in identifying patients with severe coronary lesions, left ventricular dysfunction, and extensive ischemic injury.
Abstract

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