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Updated: Mar 29, 2026

Quantification of the Immunosuppressant Tacrolimus on Dried Blood Spots Using LC-MS/MS
Published on: November 8, 2015
Tacrolimus-Induced Diabetic Ketoacidosis After Allogeneic Bone Marrow Transplant
Soner Solmaz1, Zafer Gökgöz, Çiğdem Gereklioğlu
1Department of Hematology, Başkent University, Adana, Turkey.
Abstract:
New-onset diabetes mellitus after solid-organ transplant makes for complicated tacrolimus immunosuppression. However, tacrolimus-associated diabetic ketoacidosis has not been reported in bone marrow transplant. We report 24-year-old women, hospitalized with diabetic ketoacidosis, 70 days after undergoing a bone marrow transplant with tacrolimus immunosuppression. Clinicians should be wary about tacrolimus levels and the risk of hyperglycemic states after bone marrow transplant as with other solid-organ transplants.
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