Fluorescence guided resection (FGR): A primer for oncology

Area of Science:

• Oncology
• Surgical Oncology
• Medical Imaging

Background:

• Surgical tumor removal is crucial for curative cancer treatment.
• Residual disease after surgery negatively impacts patient survival.
• Image-guided surgery techniques aim to improve tumor resection completeness.

Purpose of the Study:

• To summarize the theory and practice of Fluorescent Guided Resection (FGR).
• To review current applications of FGR in clinical oncology.
• To discuss outcomes and limitations of FGR technology.

Main Methods:

• Preoperative application of a fluorescent probe to concentrate in the tumor bed.
• Intraoperative application of specific light to induce fluorescence.
• Visualization of tumor extent using generated fluorescence during surgery.

Main Results:

• Improved visualization of tumor margins during surgery.
• Enhanced rates of complete tumor resection.
• Diminished rates of patient morbidity due to precise tissue removal.

Conclusions:

• Fluorescent Guided Resection (FGR) is a valuable image-guided surgery technique.
• FGR improves surgical outcomes in oncology by enhancing tumor visualization and resection.
• Further advancements in FGR technology and application are warranted.