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In vitro antibacterial activity of different pulp capping materials
Claudio Poggio1, Riccardo Beltrami2, Marco Colombo1
1Department of Clinical-Surgical, Diagnostic and Pediatric Sciences - Section of Dentistry, University of Pavia, Piazzale Golgi 3, 27100 Pavia, Italy.
Journal of Clinical and Experimental Dentistry
|December 9, 2015
Summary
Calcium hydroxide-based pulp capping materials exhibit superior antimicrobial activity compared to MTA-based materials. This study evaluated six materials using the agar disc diffusion test against common oral bacteria.
Area of Science:
- Dental materials science
- Microbiology
- Biomaterials
Background:
- Direct pulp capping aims to preserve dental pulp vitality by sealing exposures.
- Six pulp capping materials were assessed for antimicrobial activity: Dycal, Calcicur, Calcimol LC, TheraCal LC, MTA Angelus, and Biodentine.
Purpose of the Study:
- To evaluate and compare the antimicrobial activity of six different pulp capping materials.
- To determine the efficacy of calcium hydroxide-based and MTA-based materials against specific oral bacteria.
Main Methods:
- Agar disc diffusion test was employed to assess antimicrobial properties.
- Three bacterial strains (Streptococcus salivarius, Streptococcus sanguis, Streptococcus mutans) were used.
- Inhibition zones were measured after 24-hour incubation at 37°C.
Main Results:
- Significant differences in antibacterial properties were observed among the tested materials (ANOVA).
- MTA-based materials demonstrated smaller growth inhibition zones compared to calcium hydroxide-based materials.
Conclusions:
- Calcium hydroxide-based pulp capping materials possess higher antimicrobial activity than MTA-based materials.
- The findings provide insights into material selection for direct pulp capping procedures.

