Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Regional Terms01:12

Regional Terms

16.7K
Regional terms describe anatomy by dividing the body parts into different regions that contain structures involved in contributing similar functions. Using these terms helps increase the accurate description and identification of the particular region of interest or region affected by the disease.
Primarily, the human body has two major regions, the axial and appendicular regions. The axial region comprises regions from the head to the abdomen and makes up the central body axis. In contrast,...
16.7K
Pain01:20

Pain

1.8K
Pain serves as a critical warning signal that alerts the body to potential or actual harm. When mechanical pressure on the skin is intense, such as from a sharp pinch, the sensation transitions from touch to pain. Similarly, extreme temperatures, like a hot pot handle, convert the sensation of heat into pain. Pain can also result from overstimulation of other senses, such as blinding light, loud noise, or the intense heat from habañero peppers. This ability to sense pain is essential for...
1.8K
Local Anesthetics: Clinical Application as Intravenous Regional Anesthesia01:16

Local Anesthetics: Clinical Application as Intravenous Regional Anesthesia

1.9K
Intravenous regional anesthesia or the Bier block technique is used to anesthetize a specific limb or extremity. It uses exsanguinated or blood-drained vessels to transport local anesthetics or LAs to the peripheral nerve trunks. Lidocaine without vasoconstrictors like epinephrine is most commonly used for this technique. Other drugs used are prilocaine, ropivacaine, and chloroprocaine. Bupivacaine is not recommended for this technique due to its high cardiac toxicity.
One of the advantages of...
1.9K
Analgesia and Pain Management01:25

Analgesia and Pain Management

2.9K
Pain is critical to various clinical pathologies, provoking an urgent need for effective management. Pain, whether acute or chronic, is a complex neurochemical process. Its alleviation depends on the type, with nonopioid analgesics effective for mild to moderate pain, such as musculoskeletal or inflammatory pain, while neuropathic pain responds best to anticonvulsants, tricyclic antidepressants, or serotonin/norepinephrine reuptake inhibitors. For severe acute or chronic pain, opioids may be...
2.9K
Abdominal Regions and Quadrants01:19

Abdominal Regions and Quadrants

19.5K
To promote clear communication, for instance, about the location of a patient's abdominal pain or a suspicious mass, anatomists and clinicians typically use imaginary lines to categorize the abdominopelvic cavity into either four quadrants or nine regions to identify organs in the cavity.
The simpler quadrants approach, which is more commonly used in medicine, subdivides the cavity with one horizontal and one vertical line that intersects at the patient's umbilicus (navel). The four...
19.5K
Local Anesthetics: Differential Sensitivity of Nerve Fibers01:24

Local Anesthetics: Differential Sensitivity of Nerve Fibers

1.7K
Local anesthetics (LAs) block the sodium channels of nerve trunks, sensory nerve endings, and neuromuscular junctions. Although LAs can block all kinds of nerves, the sensitivity of nerve fibers differs according to nerve types and structures. LAs are known to block myelinated fibers faster than unmyelinated ones. Also, they block pain or sensory neurons at low concentrations without affecting the motor neurons involved in muscle contractions. This helps relieve labor pain without affecting the...
1.7K

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

An Australian survey of health professionals' perceptions of use and usefulness of electronic medical records in hospitalised children's pain care.

Journal of child health care : for professionals working with children in the hospital and community·2024
Same author

"Seeing the light in the shade of it": primary caregiver and youth perspectives on using an inpatient portal for pain care during hospitalization.

Pain·2023
Same author

Call to focus on digital health technologies in hospitalized children's pain care: clinician experts' qualitative insights on optimizing electronic medical records to improve care.

Pain·2023
Same author

A pilot study of inhaled methoxyflurane for procedural analgesia in children.

Paediatric anaesthesia·2007
Same author

Colobronchial fistula in a pediatric patient: diagnostic value of isolated single-lung ventilation and intraoperative use of high frequency oscillatory ventilation.

Anesthesia and analgesia·2002
Same journal

Dual antihypertensive fixed-dose combinations approved for first-line use on the Pharmaceutical Benefits Scheme.

Australian prescriber·2026
Same journal

Capivasertib for locally advanced or metastatic breast cancer.

Australian prescriber·2026
Same journal

Diagnosis and management of irritable bowel syndrome.

Australian prescriber·2026
Same journal

Stopping antidepressants: when and how.

Australian prescriber·2026
Same journal

Emergency contraception: an overview.

Australian prescriber·2026
Same journal

Sodium valproate: balancing benefits and risks especially in people of childbearing potential.

Australian prescriber·2026
See all related articles

Related Experiment Video

Updated: Mar 29, 2026

Chronic Post-Ischemia Pain Model for Complex Regional Pain Syndrome Type-I in Rats
07:12

Chronic Post-Ischemia Pain Model for Complex Regional Pain Syndrome Type-I in Rats

Published on: January 21, 2020

8.5K

Complex regional pain syndrome.

Greta Palmer1

  • 1Royal Children's Hospital and Royal Melbourne Hospital.

Australian Prescriber
|December 10, 2015
PubMed
Summary
This summary is machine-generated.

Complex regional pain syndrome (CRPS) is a chronic pain condition often following injury. Treatment focuses on rehabilitation and movement, with psychological support and pharmacotherapy aiding functional improvement.

Keywords:
analgesicsanticonvulsantsantidepressantscomplex regional pain syndromes

More Related Videos

Author Spotlight: Regenerative Peripheral Nerve Interface (RPNI) Surgery in Postamputation Pain Management
03:53

Author Spotlight: Regenerative Peripheral Nerve Interface (RPNI) Surgery in Postamputation Pain Management

Published on: March 15, 2024

3.2K
Subcutaneous Trigeminal Nerve Field Stimulation for Refractory Facial Pain
09:35

Subcutaneous Trigeminal Nerve Field Stimulation for Refractory Facial Pain

Published on: May 10, 2017

19.8K

Related Experiment Videos

Last Updated: Mar 29, 2026

Chronic Post-Ischemia Pain Model for Complex Regional Pain Syndrome Type-I in Rats
07:12

Chronic Post-Ischemia Pain Model for Complex Regional Pain Syndrome Type-I in Rats

Published on: January 21, 2020

8.5K
Author Spotlight: Regenerative Peripheral Nerve Interface (RPNI) Surgery in Postamputation Pain Management
03:53

Author Spotlight: Regenerative Peripheral Nerve Interface (RPNI) Surgery in Postamputation Pain Management

Published on: March 15, 2024

3.2K
Subcutaneous Trigeminal Nerve Field Stimulation for Refractory Facial Pain
09:35

Subcutaneous Trigeminal Nerve Field Stimulation for Refractory Facial Pain

Published on: May 10, 2017

19.8K

Area of Science:

  • Pain Medicine
  • Neurology
  • Rehabilitation Medicine

Background:

  • Complex regional pain syndrome (CRPS) is an uncommon chronic pain condition.
  • It can develop spontaneously or after an injury, characterized by limb pain, sensory abnormalities, and motor and trophic changes.
  • Diagnosis is clinical and requires exclusion of other conditions.

Purpose of the Study:

  • To provide an overview of complex regional pain syndrome (CRPS).
  • To discuss the diagnostic criteria and therapeutic approaches for CRPS.
  • To highlight the role of rehabilitation, pharmacotherapy, and psychological interventions.

Main Methods:

  • Clinical diagnosis based on characteristic symptoms and exclusion.
  • Emphasis on graded rehabilitation, physiotherapy, and occupational therapy.
  • Pharmacotherapy includes analgesia, antineuropathic drugs, corticosteroids, calcitonin, and bisphosphonates.

Main Results:

  • CRPS presents with pain, allodynia, hypersensitivity, hyperalgesia, vasomotor, sudomotor, and motor abnormalities, and trophic changes.
  • Effective management involves physiotherapy, occupational therapy, and psychological support.
  • Pharmacological options aim to improve function, with varying evidence for different agents.

Conclusions:

  • Early and graded rehabilitation is the cornerstone of CRPS management.
  • Psychological therapies are crucial, especially in the chronic phase and for patients with slow progress.
  • While Vitamin C may aid prevention, it lacks evidence for treating established CRPS.