Related Experiment Video
Updated: Mar 29, 2026

An Inertial Measurement Unit Based Method to Estimate Hip and Knee Joint Kinematics in Team Sport Athletes on the Field
Published on: May 26, 2020
Preseason preparation training and endothelial function in elite professional soccer players
Nikolaos E Androulakis1, Nikolaos E Koundourakis2, Eleni Nioti1
1Hematology Laboratory, Iraklion University Hospital, Iraklion, Greece.
Aim:
To examine whether a high volume of soccer-specific training can lead to endothelial activation and/or dysfunction in professional soccer players due to exercise-induced oxidative stress.
Methods:
Twenty-three (15 nonsmokers and eight smokers) healthy, elite male professional soccer players (mean age: 25.2±4.3 years, BMI: 23.1±1.3 kg/m(2), fat: 7.8%±2.6%) were selected for this study. All participants had a full clinical and laboratory evaluation. von Willebrand factor antigen (vWf Ag) plasma levels were measured on two different occasions: 1 day before the beginning of the preseason preparation period and after 7 weeks of strenuous exercise.
Results:
Mean vWf Ag plasma levels were significantly decreased from 95.1%±26% to 88.3%±27.2% at the end of the experimental period (P=0.018), suggesting a potential beneficial effect on the endothelium of these athletes. Further analysis showed that age greater than 29 years with an age range from 29 to 34 years can not impair this effect (P>0.05).
Conclusion:
Strenuous exercise did not lead to endothelium activation or dysfunction in well-trained elite soccer players. On the contrary, it seemed to produce a beneficial effect on the endothelium of these players.
More Related Videos
Related Concept Videos
Exercise and Cardiovascular Response
Light to moderate physical activity initiates a series of interconnected responses in the body. The heart rate modestly increases in anticipation of the workout, followed by widespread vasodilation as oxygen consumption by skeletal muscles increases. This results in decreased peripheral resistance, increased capillary blood flow, and accelerated...
Exercise and Cardiac Output
Sustained exercise increases the muscles' oxygen demand, which can be...

