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Updated: Mar 29, 2026

Author Spotlight: Computing the Effects of a Local Radiofrequency Hyperthermia Intervention on Tumor Biomechanics
Published on: December 1, 2023
Two 27 MHz Simple Inductive Loops, as Hyperthermia Treatment Applicators: Theoretical Analysis and Development
Vassilis Kouloulias1, Irene Karanasiou2, Maria Koutsoupidou2
12nd Department of Radiology, ATTIKON University Hospital, Medical School, University of Athens, Rimini 1, Haidari, 124 64 Athens, Greece ; Microwave and Fiber Optics Laboratory, School of Electrical and Computer Engineering, Institute of Communication and Computer Systems, National Technical University of Athens, Heroon Polytechniou 9, 15780 Zografou, Greece ; 1st Department of Radiology, Aretaieion University Hospital, Medical School, University of Athens, Vassilissis Sofias 76, 115 28 Athens, Greece.
This study developed and tested inductive loop antennas for hyperthermia treatment. The simple loop applicators demonstrated efficient peripheral heating for tumors at a depth of 2-3.5 cm.
Area of Science:
- Medical Physics
- Biomedical Engineering
- Electromagnetics
Background:
- Deep heating remains a key research area in hyperthermia treatment.
- Developing effective heating applicators is crucial for therapeutic outcomes.
Purpose of the Study:
- To design, develop, and analyze a simple loop antenna as a heating applicator for hyperthermia.
- To evaluate the performance of inductive loop antennas for targeted tissue heating.
Main Methods:
- Two inductive loop antennas (7 cm and 9 cm radii) were designed, simulated, and constructed for 27 MHz operation.
- Theoretical analysis employed Green's and Bessel's functions.
- Experimental validation was conducted using phantom models radiated by the antennas.
Main Results:
- Specific absorption rate (SAR) distributions were correlated with phantom temperature measurements.
- Theoretical, simulation, and experimental results showed good agreement.
- Achieved penetration depth was measured to be between 2-3.5 cm.
Conclusions:
- Inductive current loops are effective applicators for peripheral hyperthermia.
- The developed loop antennas are suitable for treating spherical tumor formations at depths of 2-3.5 cm.
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