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Pain mechanisms underlying vascular headaches. Progress Report 1989
M A Moskowitz1, M G Buzzi, D E Sakas
1Stroke Research Laboratory, Massachusetts General Hospital, Harvard Medical School, Boston 02114.
Revue Neurologique
|January 1, 1989
Summary
Vascular headaches involve cephalic blood vessels and sensory nerves. This review explores the trigeminovascular system, a key pathway in headache pathophysiology.
Area of Science:
- Neurology
- Vascular Biology
- Pain Research
Background:
- Vascular headaches are common neurological issues.
- Cephalic blood vessels are primary headache sources.
- Sensory nerves release neuropeptides causing vasodilation and pain.
Purpose of the Study:
- To review the trigeminovascular system's role in headache.
- To update knowledge on headache pathophysiology.
Main Methods:
- Literature review of vascular headache mechanisms.
- Analysis of the trigeminovascular system's function.
Main Results:
- The trigeminovascular system is a common pain pathway.
- This system explains pain referral and drug actions.
- It suggests local mechanisms for enhanced blood flow.
Conclusions:
- The trigeminovascular system is central to vascular headaches.
- Understanding this system clarifies headache patterns and treatments.