An overview of human arterial pathology
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1Department of Pathology, St. Luke's Episcopal Hospital, Houston, Texas 77030.
Insights
This review details the pathology of human arterial diseases, covering atherosclerosis, aortitis, arteritis, aneurysms, and congenital conditions. It also summarizes vascular changes caused by drugs or toxins.
Area of Science:
- Cardiovascular Pathology
- Vascular Biology
- Human Pathology
Background:
- Human arterial diseases represent a significant global health burden.
- Understanding the gross and microscopic characteristics of these conditions is crucial for diagnosis and treatment.
- A comprehensive review of arterial pathologies, from common to rare, is needed.
Purpose of the Study:
- To review the pathology of major human arterial diseases.
- To describe atherosclerotic lesions, aortitis, arteritis, and dissecting aneurysms.
- To cover rarer conditions and drug/toxin-induced vascular changes.
Main Methods:
- Review of existing literature on human arterial diseases.
- Description of gross and microscopic pathological characteristics.
- Inclusion of common and rare arterial conditions, as well as toxicological effects.
Main Results:
- Detailed descriptions of common atherosclerotic-related lesions in the aorta, coronary, and peripheral arteries.
- Characterization of various forms of aortitis, arteritis, and dissecting aneurysms.
- Summary of congenital hypoplasia and morphologic changes due to drugs or toxins.
Conclusions:
- This review provides a comprehensive overview of human arterial disease pathology.
- It highlights the spectrum of conditions affecting arteries, aiding in understanding their diverse manifestations.
- The information is valuable for pathologists, clinicians, and researchers in cardiovascular medicine.
Abstract:
In this manuscript the pathology of human arterial disease, including diseases of the aorta, coronary arteries, and peripheral arteries, is reviewed. Common atherosclerotic-related lesions and varied forms of aortitis, arteritis, and dissecting aneurysms are described in terms of their gross and microscopic characteristics. In addition, rarer occurrences, such as congenital hypoplasia of the arteries, are mentioned. Finally, morphologic changes in blood vessels that have been affected by drugs or toxins are summarized.