Related Experiment Video
Updated: Mar 29, 2026

Improving IV Insulin Administration in a Community Hospital
Published on: June 11, 2012
Insulin pumps: Beyond basal-bolus.
Richard Millstein1, Nancy Mora Becerra2, Jay H Shubrook3
1Department of Endocrinology, University of Colorado, Denver, CO, USA.
Insulin pumps offer advanced diabetes management, improving insulin dosing accuracy and flexibility. They are a preferred treatment for type 1 and type 2 diabetes patients requiring basal-bolus insulin therapy.
Area of Science:
- Endocrinology
- Metabolic Diseases
- Biomedical Engineering
Background:
- Insulin pumps represent a significant advancement in diabetes care.
- They offer improved accuracy, flexibility, and safety for insulin delivery.
- Basal-bolus insulin therapy is crucial for many individuals with diabetes.
Purpose of the Study:
- To review the fundamental principles of insulin pump operation.
- To identify patient populations who benefit from insulin pump therapy.
- To outline management strategies for inpatients and outpatients using insulin pumps.
Main Methods:
- Literature review on insulin pump technology and clinical application.
- Analysis of benefits, safety, and efficacy data for insulin pump users.
- Examination of inpatient and outpatient management protocols.
Main Results:
- Insulin pumps enhance the ease and precision of insulin dosing.
- They provide significant flexibility, safety, and efficacy for basal-bolus therapy.
- Preferred treatment for type 1 diabetes and many type 2 diabetes patients.
Conclusions:
- Insulin pump therapy is a cornerstone of modern diabetes management.
- Understanding pump function and management is key for healthcare providers.
- This review provides essential information for optimizing insulin pump use in diverse patient settings.
Related Concept Videos
Insulin: Dosing Regimen and Adverse Effects
The basal dose constitutes about 40%-50% of the total daily dose, with the rest as premeal insulin. The mealtime insulin dose should mirror...
Insulin Formulations: Types and Delivery
Short-acting insulins are divided into...
Insulin: Biosynthesis, Chemistry, and Preparation
Damage or functional impairment of β-cells inhibits insulin production, leading to diabetes. Diabetes treatment...
Glucose Homeostasis: Pancreatic Islets and Insulin Secretion
Insulin and C-peptide are...
Glucagon-like Receptor Agonists
GLP-1, when administered in high doses intravenously, triggers insulin secretion, inhibits glucagon release, slows gastric emptying, reduces food intake, and restores normal insulin secretion. However, its rapid inactivation by...
Diabetes: Management and Pharmacotherapy
Insulin remains the cornerstone of treatment for most patients with type 1 and many...

