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Preeclampsia transforms membrane N-glycome in human placenta

Dragana Robajac1, Valerie Vanhooren2, Romana Masnikosa1

  • 1Institute for the Application of Nuclear Energy - INEP, University of Belgrade, Belgrade 381, Serbia.

Experimental and Molecular Pathology
|December 15, 2015
PubMed
Summary

Preeclampsia with foetal growth restriction alters placental N-glycans, reducing fucosylation and increasing simpler mannose structures. Specific receptor changes, like reduced sialylation on the insulin receptor, highlight the need for targeted glycoprotein analysis.

Keywords:
DSA-FACEGlycosylationIGF1RIRIUGRPlacental membranePreeclampsia

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