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Updated: Mar 28, 2026

Proton Therapy Delivery and Its Clinical Application in Select Solid Tumor Malignancies
Published on: February 6, 2019
MEASUREMENT OF SECONDARY NEUTRONS GENERATED DURING PROTON THERAPY.
Z Vykydal1, M Andrlík2, H Bártová3
1Czech Metrology Institute, Radiová 1a, Praha 10 102 00, Czech Republic zvykydal@cmi.cz.
This study measured secondary neutron radiation during proton therapy. Results help assess patient risks from neutrons generated by phantoms and range shifters, crucial for radiation safety.
Area of Science:
- Medical Physics
- Radiation Dosimetry
- Nuclear Engineering
Background:
- Proton therapy offers precise radiation delivery but can generate secondary neutrons.
- Understanding neutron radiation is vital for patient safety and treatment optimization.
- Secondary neutrons pose a potential risk to patients and medical staff.
Purpose of the Study:
- To evaluate patient exposure risks to secondary neutrons during proton therapy.
- To quantify neutron spectral fluences generated by phantoms and range shifters.
- To determine the contribution of treatment components to neutron production.
Main Methods:
- Utilized an extended Bonner sphere spectrometer (EBS) for neutron spectral fluence measurements.
- Employed passive thermoluminescent detectors (TLDs) with 6LiF and 7LiF chips.
- Conducted measurements behind a Nylon 6 phantom and near a range shifter irradiated with 200 MeV protons.
Main Results:
- Presented secondary neutron spectral fluences measured by the EBS.
- Quantified neutron generation from both the Nylon 6 phantom and the range shifter.
- Calculated effective dose values derived from the measured neutron spectral fluences.
Conclusions:
- Provided essential data for assessing secondary neutron risks in proton therapy.
- Highlighted the role of phantoms and range shifters in neutron production.
- Contributed to improving radiation safety protocols in proton therapy centers.
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