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A baby with a lot of nerve

Hema L Ramkumar1, Rohan Verma2, Janet Crow3

  • 1Department of Ophthalmology, University of California, San Diego, San Diego, California, USA.

Survey of Ophthalmology
|December 15, 2015
PubMed

Insights

Pseudotumor cerebri (PTC) in infants is rare, often linked to various health issues. This case highlights PTC in an infant caused by vitamin A toxicity from a common prenatal vitamin.

Area of Science:

  • Pediatric Ophthalmology
  • Neurology
  • Toxicology

Background:

  • Pseudotumor cerebri (PTC), or idiopathic intracranial hypertension, is a rare condition in infants.
  • PTC in infants is associated with endocrine disorders, medications, infections, systemic conditions, and nutritional factors like vitamin A toxicity.

Observation:

  • A case of an infant presenting with bilateral disk edema and acute left sixth cranial nerve (CN VI) palsy was observed.
  • The infant was diagnosed with pseudotumor cerebri (PTC).

Findings:

  • The infant's PTC was linked to hypervitaminosis A.
  • The source of excessive vitamin A was identified as a common prenatal vitamin supplement.

Implications:

  • This case underscores the potential risk of vitamin A toxicity from prenatal vitamins in infants.
  • Clinicians should consider hypervitaminosis A when evaluating infants with PTC, even from seemingly innocuous sources.
  • Awareness of this association is crucial for preventing and diagnosing PTC in pediatric populations.

Keywords:
acetazolamidecranial neuropathyidiopathic intracranial hypertensioninfantpseudotumor cerebrivitamin A

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