Search research articles

ABOUT JoVE

Overview Leadership Blog JoVE Help Center

AUTHORS

Publishing Process Editorial Board Scope & Policies Peer Review FAQ Submit

LIBRARIANS

Testimonials Subscriptions Access Resources Library Advisory Board FAQ

RESEARCH

JoVE Journal Methods Collections JoVE Encyclopedia of Experiments Archive

EDUCATION

JoVE Core JoVE Business JoVE Science Education JoVE Lab Manual Faculty Resource Center Faculty Site

Terms & Conditions of Use

Related Concept Videos

Infectious Diseases and Their Occurrence

Infectious Diseases and Their Occurrence

Infectious diseases appear in populations through various transmission patterns, influenced by pathogen characteristics, population immunity, environmental conditions, and social behavior. Understanding these patterns is essential for effective public health surveillance and intervention. These categories—sporadic, outbreak, epidemic, pandemic, and endemic—help frame the nature and scope of disease events.Sporadic diseases occur irregularly and infrequently, without a predictable temporal or...

Reservoir of Infection

Reservoir of Infection

Infectious diseases arise from intricate interactions between pathogens and their reservoirs. A reservoir of infection refers to the natural habitat where a pathogen lives, grows, and multiplies, serving as a continual source of infection. Reservoirs are broadly classified as either living or nonliving, and each plays a unique role in disease transmission, significantly influencing public health interventions and control strategies.Humans act as reservoirs for a wide array of pathogens,...

Rocky Mountain Spotted Fever

Rocky Mountain Spotted Fever

Rocky Mountain Spotted Fever (RMSF) is a severe tick-borne illness caused by Rickettsia rickettsii, a Gram-negative, coccobacillary bacterium. This pathogen is an obligate intracellular parasite, requiring a host cell for replication. Transmission occurs through the bite of an infected tick. In the United States, the most important vectors are Dermacentor variabilis (American dog tick) and Dermacentor andersoni (Rocky Mountain wood tick), though other tick species may also serve as vectors.

Rabies

Rabies

Rabies is a lethal zoonotic disease caused by a single-stranded, negative-sense RNA virus of the Lyssavirus genus, within the family Rhabdoviridae. Its primary mode of transmission to humans is through bites or saliva-contaminated scratches from infected mammals such as dogs, bats, raccoons, or foxes. Transmission can also occur if infectious saliva contacts abraded skin or intact mucous membranes, including the conjunctiva.Viral Entry and Early ReplicationOnce introduced at the bite or scratch...

Arboviral Encephalitis

Arboviral Encephalitis

Arboviral encephalitis refers to brain inflammation caused by arthropod-borne viruses, particularly those transmitted through mosquito vectors. Among these, West Nile virus (WNV), a member of the Flaviviridae family, is a significant public health concern. WNV is an enveloped, positive-sense, single-stranded RNA virus. Human infection typically begins when an infected mosquito introduces the virus into the dermis during feeding. The primary transmission cycle involves birds as amplifying hosts...

Toxoplasmosis

Toxoplasmosis

Toxoplasmosis, a zoonotic disease caused by the protozoan Toxoplasma gondii, poses significant public health challenges globally due to its high seroprevalence and varied clinical manifestations. As an obligate intracellular parasite, T. gondii can infect all warm-blooded vertebrates, but felids are its only definitive hosts, shedding unsporulated oocysts into the environment. Humans typically acquire the infection through ingestion of tissue cysts in undercooked meat or oocysts from...

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by

Same author

[Progressive human viral encephalitis associated to a bat bite].

Neurologia (Barcelona, Spain)·2006

Same author

Progressive multifocal leukoencephalopathy: clinical description and demonstration of the causal agent.

Neurologia (Barcelona, Spain)·2005

Same author

Miliary tuberculosis involving the central nervous system.

Neurologia (Barcelona, Spain)·2005

Same author

Update on sporotrichosis.

Australian family physician·1995

Same author

[The immunology of cholera and the molecular biology of cholera toxin. Recent progress and future perspectives].

Revista alergia Mexico (Tecamachalco, Puebla, Mexico : 1993)·1994

Same author

[Coccidioidomycosis in children].

Boletin medico del Hospital Infantil de Mexico·1989

Search research articles

Related Experiment Video

Updated: Jul 20, 2026

Field Postmortem Rabies Rapid Immunochromatographic Diagnostic Test for Resource-Limited Settings with Further Molecular Applications

Field Postmortem Rabies Rapid Immunochromatographic Diagnostic Test for Resource-Limited Settings with Further Molecular Applications

Published on: June 29, 2020

[Rabies as a public health problem].

T Carrada-Bravo

Boletin Medico Del Hospital Infantil De Mexico

|June 1, 1989

Summary

Rabies virus, a Rhabdoviridae family member, spreads via neural pathways, causing animal fury and biting. Prompt postexposure treatment, including wound cleaning and immunization, is crucial for preventing human rabies infection.

Area of Science:

Virology: Rabies virus structure and replication cycle.
Epidemiology: Rabies prevalence and transmission dynamics in Mexico.
Immunology: Host immune response evasion and postexposure prophylaxis.

Context:

Rabies remains a significant public health and economic burden in Mexico, with urban rabies predominating.
Historical data indicates substantial human mortality and animal cases, necessitating extensive postexposure vaccinations.
Understanding viral transmission pathways, including neural spread and salivary gland involvement, is key to control.

Purpose:

To describe the rabies virus (Rhabdoviridae) structure, transmission, and clinical manifestations.
To highlight the public health impact of rabies in Mexico, citing historical human and animal case data.
To outline essential postexposure prophylaxis strategies, emphasizing prompt wound care and immunization.

More Related Videos

A Trap-Vaccinate-Release Protocol for Immunization of Skunks and Additional Rabies Vectors Against Rabies

A Trap-Vaccinate-Release Protocol for Immunization of Skunks and Additional Rabies Vectors Against Rabies

Published on: November 29, 2024

Whole Genome Sequencing for Rapid Characterization of Rabies Virus Using Nanopore Technology

Whole Genome Sequencing for Rapid Characterization of Rabies Virus Using Nanopore Technology

Published on: August 18, 2023

Related Experiment Videos

Last Updated: Jul 20, 2026

Field Postmortem Rabies Rapid Immunochromatographic Diagnostic Test for Resource-Limited Settings with Further Molecular Applications

Field Postmortem Rabies Rapid Immunochromatographic Diagnostic Test for Resource-Limited Settings with Further Molecular Applications

Published on: June 29, 2020

A Trap-Vaccinate-Release Protocol for Immunization of Skunks and Additional Rabies Vectors Against Rabies

A Trap-Vaccinate-Release Protocol for Immunization of Skunks and Additional Rabies Vectors Against Rabies

Published on: November 29, 2024

Whole Genome Sequencing for Rapid Characterization of Rabies Virus Using Nanopore Technology

Whole Genome Sequencing for Rapid Characterization of Rabies Virus Using Nanopore Technology

Published on: August 18, 2023

Summary:

Rabies virus, characterized by its RNA core and glycoprotein envelope, spreads via neural pathways, evading immune responses and causing characteristic animal behaviors.
Mexico faces a persistent rabies problem, particularly in urban areas, with significant human deaths and animal cases historically recorded.
Effective rabies control relies on prompt postexposure treatment, including thorough wound cleansing and combined active and passive immunization, alongside animal vaccination and public awareness.

Impact:

Informed public health strategies for rabies prevention and control in endemic regions.
Guidelines for effective postexposure prophylaxis, potentially reducing human rabies incidence.
Recommendations for veterinary surveillance and public education campaigns to mitigate rabies transmission risks.