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Disorders of coagulation in pregnancy
1Department of Anesthesiology, Icahn School of Medicine at Mount Sinai, New York, NY 10029, USA daniel.katz@mountsinai.org.
British Journal of Anaesthesia
|December 15, 2015
Summary
Pregnancy significantly alters coagulation, impacting anesthetic safety for labor and delivery. Understanding these hemostasis changes and associated disorders is vital for obstetric anesthesia providers.
Area of Science:
- Obstetrics and Gynecology
- Anesthesiology
- Hematology
Background:
- Physiological changes during pregnancy complicate normal hemostasis.
- Anesthetic management for labor and delivery requires understanding these hemostatic alterations.
- Coagulation status impacts the safety of neuraxial anesthesia in parturients.
Purpose of the Study:
- To analyze current coagulation theories in the context of pregnancy.
- To review physiological changes in coagulation during pregnancy.
- To examine common and rare coagulation disorders and their implications for neuraxial anesthesia.
Main Methods:
- Review of current literature on coagulation and pregnancy.
- Analysis of physiological adaptations in the parturient's hemostatic system.
- Examination of diagnostic methods for evaluating coagulation.
Main Results:
- Pregnancy induces significant, complex physiological changes affecting hemostasis.
- Various coagulation disorders, including von Willebrand disease and platelet issues, present unique challenges.
- The parturient's coagulation status directly influences the risks associated with neuraxial anesthesia.
Conclusions:
- A thorough understanding of pregnancy-related hemostasis is essential for safe anesthetic practice.
- Knowledge of coagulation disorders is critical for appropriate management in obstetric anesthesia.
- Evaluating coagulation effectively aids in optimizing anesthetic choices for labor and delivery.
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