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Updated: Mar 28, 2026

Large Scale Non-targeted Metabolomic Profiling of Serum by Ultra Performance Liquid Chromatography-Mass Spectrometry UPLC-MS
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Large Scale Non-targeted Metabolomic Profiling of Serum by Ultra Performance Liquid Chromatography-Mass Spectrometry UPLC-MS

Published on: March 14, 2013

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High-Resolution Mass Spectrometry for Untargeted Drug Screening.

Alan H B Wu1, Jennifer Colby2

  • 1Department of Laboratory Medicine, San Francisco General Hospital, University of California, San Francisco, San Francisco, CA, USA. wualan@labmed2.ucsf.edu.

Methods in Molecular Biology (Clifton, N.J.)
|December 15, 2015
PubMed
Summary

High-resolution mass spectrometry (HR-MS) enhances clinical toxicology by enabling presumptive identification of unknown drugs and metabolites without library matching. This advanced technique expands detection capabilities for comprehensive patient care.

Keywords:
Exact molecular formulaHigh-resolution mass spectrometryOrbitrapTime-of-flight mass spectrometryUntargeted mass screening

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