IgG4-Related Prostatitis Impairs Objective Urinary Function as with Benign Prostate Hyperplasia: A Case Report...

Area of Science:

• Urology
• Immunology
• Pathology

Background:

• IgG4-related prostatitis is a rare condition presenting with lower urinary tract symptoms.
• It can be misdiagnosed as benign prostatic hyperplasia, delaying appropriate treatment.

Purpose of the Study:

• To report a successful treatment of IgG4-related prostatitis using transurethral resection of the prostate (TUR-P).
• To highlight the importance of recognizing IgG4-related prostatitis for effective patient management.

Main Methods:

• A case report of a 47-year-old male with a history of autoimmune pancreatitis and sclerosing cholangitis.
• Initial diagnosis of benign prostatic hyperplasia based on imaging and uroflowmetry.
• Treatment with TUR-P after medical management failed.

Main Results:

• Pathological examination confirmed dense lymphoplasmacytic inflammation with numerous IgG4-positive cells, diagnosing IgG4-related prostatitis.
• Postoperative urinary function dramatically improved.
• Good urinary function was maintained for 3 years without further intervention.

Conclusions:

• Transurethral resection of the prostate (TUR-P) is an effective treatment for IgG4-related prostatitis.
• Accurate diagnosis and understanding the impact of IgG4-related prostatitis on urinary function are crucial for successful treatment.