Related Experiment Video
Updated: Mar 28, 2026

Preoxygenation Techniques for Tracheal Intubation in Critically Ill Adults Utilizing Oxygen Mask and Noninvasive Ventilation
Published on: December 5, 2025
Domiciliary noninvasive positive airway pressure therapy in children
Reshma Amin1,2,3, Suhail Al-Saleh1,2,4, Indra Narang1,2,4
1Division of Respiratory Medicine, The Hospital for Sick Children, Toronto, Canada.
Insights
Pediatric noninvasive positive airway pressure (PAP) therapy is increasingly used for various respiratory conditions beyond obstructive sleep apnea. This review covers essential considerations for pediatric pulmonologists managing children on PAP therapy.
Area of Science:
- Pediatric Pulmonology
- Respiratory Medicine
- Sleep Medicine
Background:
- Noninvasive positive airway pressure (PAP) therapy use in children has significantly increased over recent decades.
- Initial indications focused on obstructive sleep apnea, but now encompass central hypoventilation, neuromuscular disorders, and primary respiratory diseases.
Purpose of the Study:
- To provide pediatric pulmonologists with a comprehensive overview of noninvasive positive airway pressure (PAP) therapy in children.
- To cover indications, technical aspects, safety, complications, and adherence factors for pediatric PAP therapy.
Main Methods:
- This is a review article.
- It synthesizes current knowledge on pediatric noninvasive positive airway pressure (PAP) therapy.
Main Results:
- The scope of PAP therapy in pediatric respiratory care has expanded significantly.
- Effective management requires familiarity with diverse indications, devices, interfaces, and potential complications.
Conclusions:
- Pediatric pulmonologists must be well-versed in the expanding applications and management of noninvasive positive airway pressure (PAP) therapy.
- Understanding indications, settings, complications, and adherence is crucial for optimal patient outcomes.
Abstract:
There has been a dramatic increase in the past few decades in the number of children receiving noninvasive positive airway pressure (PAP) therapy at home. Although PAP therapy was first prescribed for children with obstructive sleep apnea, the indications have rapidly widened to include treatment for central hypoventilation syndromes, neuromuscular and chest wall disorders as well as primary respiratory diseases. Given the rapidly expanding use of PAP therapy in children, pediatric pulmonologists need to be familiar with the indications, technical and safety considerations as well as potential complications and challenges that may arise when caring for children using PAP therapy. This review article covers the definition of PAP therapy, modes, interfaces, devices, indications, contraindications, suggested settings, complications as well as the factors influencing the adherence.
Related Concept Videos
Mechanical Ventilation III: Noninvasive Ventilation
Noninvasive Positive-Pressure Ventilation...
Mechanical Ventilation II: Invasive Ventilation
Negative-Pressure Ventilators
Negative-pressure ventilators create a vacuum around the chest or body to draw air into the lungs, simulating breathing. This method does not require an...
Mechanical Ventilation I: Indication and Settings
Cardiopulmonary Resuscitation II: ACLS Airway Management
Ventilatory Modes
There are three ventilatory modes: full support, partial support, and spontaneous. These are described below.
Full Support Modes
Full support modes include controlled mechanical ventilation, continuous mandatory...
Inhaled Medications

