Diterpenoids from the Roots of Salvia yunnanensis
Fan Xia1, Chun-Yan Wu2, Xing-Wei Yang2
1School of Pharmaceutical Science and Yunnan Key Laboratory of Pharmacology of Natural Products, Kunming Medical University, Kunming, 650500, People's Republic of China.
Natural Products and Bioprospecting
|December 16, 2015
Abstract:
Two new diterpenoids, salyunnanins I and J (1 and 2), together with ten analogues, were isolated from the roots of Salvia yunnanensis. The structures of the new isolates, possessing different neo-clerodane and seco-abietane diterpenoid skeletons respectively, were elucidated on the basis of comprehensive spectroscopic data. All of the compounds were tested for the inhibitory activities against six human tumor lines in vitro, and several ones showed moderate cytotoxic activities.
