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Gallbladder paraganglioma
İlhan Ece1, Hüsnü Alptekin1, Zeliha Esin Çelik2
1Department of General Surgery, Selçuk University Faculty of Medicine, Konya, Turkey.
Ulusal Cerrahi Dergisi
|December 16, 2015
Summary
Gallbladder paraganglioma, a rare tumor, can present with symptoms like right upper quadrant pain. This case highlights the importance of thorough pathological examination for accurate diagnosis of this unusual gallbladder neoplasm.
Area of Science:
- Oncology
- Pathology
Background:
- Gallbladder paragangliomas are exceedingly rare neuroendocrine tumors, with limited documented cases.
- Most reported instances are incidental findings, often asymptomatic.
Observation:
- A 57-year-old female presented with intermittent right upper quadrant pain.
- Preoperative imaging revealed a gallbladder neck mass, initially suspected as benign.
Findings:
- Postoperative histopathology confirmed gallbladder paraganglioma alongside chronic cholecystitis.
- Immunohistochemistry showed characteristic vimentin, synaptophysin, and S-100 positivity in tumor cells.
Implications:
- This case underscores the necessity of comprehensive pathological evaluation for rare gallbladder tumors.
- Highlights the potential for symptomatic presentation of gallbladder paraganglioma, contrary to typical asymptomatic findings.
