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Using a Murine Model of Psychosocial Stress in Pregnancy as a Translationally Relevant Paradigm for Psychiatric Disorders in Mothers and Infants
Published on: June 13, 2021
Using clinical decision support as a means of implementing a universal postpartum depression screening program.
Holly Loudon1, Farida Nentin1, Michael E Silverman2
1Department of Obstetrics, Gynecology and Reproductive Science, Icahn Medical School at Mount Sinai Hospital, New York, NY, USA.
Implementing clinical decision support (CDS) in electronic health records (EHR) effectively screened nearly all mothers for postpartum depression (PPD). This technology addresses key barriers in identifying PPD symptoms for better maternal mental health care.
Area of Science:
- Medical Informatics
- Public Health
- Obstetrics and Gynecology
Background:
- Postpartum depression (PPD) diagnosis is hindered by low awareness, varied symptoms, and diverse screening methods.
- Effective symptom detection remains a significant challenge for healthcare providers managing maternal mental health.
Purpose of the Study:
- To evaluate the feasibility of integrating clinical decision support (CDS) into electronic health records (EHR) for universal postpartum depression (PPD) screening.
- To implement a standardized PPD screening program in a large, high-risk population.
Main Methods:
- A CDS "hard stop" was integrated into the EHR at an OB/GYN practice, prompting clinicians to administer the Edinburgh Postnatal Depression Scale (EPDS).
- The study included all women attending postpartum care between 2010 and 2013.
Main Results:
- The CDS module successfully screened 99.5% of 2102 women for PPD.
- Only 0.5% of screens were missed due to patient refusal, language barriers, or EHR clarity issues.
Conclusions:
- Clinical decision support (CDS) integrated into EHRs is a feasible and effective strategy to overcome barriers in postpartum depression (PPD) symptom identification.
- This technological approach facilitates universal, standardized PPD screening at the practitioner level, improving maternal mental health surveillance.
Related Concept Videos
Depressive Disorders: MDD and Dysthymia
Depression: Overview

