Primary gallbladder lymphoma presenting with perforated cholecystitis and hyperamylasaemia
K S V Shah1, V G Shelat1, S Jogai1
1University Hospital Southampton NHS Foundation Trust , UK.
Annals of the Royal College of Surgeons of England
|December 18, 2015
Summary
Primary gallbladder lymphoma is rare and can cause perforated cholecystitis. This case report details an elderly woman with acute abdomen, revealing marginal zone lymphoma in the gallbladder upon surgical examination.
Area of Science:
- Gastroenterology
- Oncology
- Surgical Pathology
Background:
- Primary gallbladder lymphoma is an exceptionally rare malignancy.
- Perforated cholecystitis is typically associated with gallstones, not lymphoma.
- Chemotherapy-induced complications can mimic other pathologies.
Observation:
- An 80-year-old woman presented with acute abdomen and peritonitis.
- Computed tomography showed generalized free fluid but was inconclusive regarding the gallbladder pathology.
- Elevated serum amylase levels were noted, with a normal pancreas on imaging.
Findings:
- Emergency laparotomy revealed a distended gallbladder with a necrotic patch and bilious peritonitis.
- Histological examination of the gallbladder confirmed the presence of marginal zone lymphoma.
- This represents a unique presentation of gallbladder perforation secondary to primary lymphoma.
Implications:
- Highlights the importance of considering rare diagnoses in acute abdominal presentations.
- Underscores the need for thorough histological examination of the gallbladder in cases of perforation.
- Adds to the limited literature on non-chemotherapy-related gallbladder perforation due to lymphoma.
More Related Videos
Related Concept Videos
01:24Chronic Pancreatitis I: Introduction
881
The pancreas, an elongated and flat gland situated behind the stomach, serves a vital function in digesting food and managing blood sugar levels.
Pancreatitis is the inflammation of the pancreas, which occurs when the immune system becomes active and causes swelling, pain, and disruptions in organ function. Pancreatitis can manifest as either an acute or chronic condition.
Acute pancreatitis arises suddenly and lasts for a brief duration, while chronic pancreatitis is a long-term affliction...
Pancreatitis is the inflammation of the pancreas, which occurs when the immune system becomes active and causes swelling, pain, and disruptions in organ function. Pancreatitis can manifest as either an acute or chronic condition.
Acute pancreatitis arises suddenly and lasts for a brief duration, while chronic pancreatitis is a long-term affliction...
881
01:30Acute Pancreatitis II: Clinical Manifestations and Management
1.1K
Acute pancreatitis presents a complex medical emergency characterized by rapid onset inflammation of the pancreas, demanding timely diagnosis and management to prevent complications. The condition primarily manifests through severe upper abdominal pain that often radiates to the back. This pain intensifies following the consumption of fatty foods. Accompanying symptoms such as nausea, vomiting, abdominal distention, fever, dyspnea, cyanosis, and jaundice can vary in intensity but significantly...
1.1K
01:17Gallbladder
3.1K
The gallbladder is a small, pear-shaped organ that plays a crucial role in our digestive system. Measuring about 10 cm in length, it is comparable in size to a kiwi fruit and is located in a hollow area on the lower surface of the liver. The gallbladder's primary function is to store and concentrate bile, a fluid produced by the liver that aids in digestion.
The gallbladder's anatomy consists of three regions: the fundus, body, and neck. Extending from the neck, the cystic duct joins...
The gallbladder's anatomy consists of three regions: the fundus, body, and neck. Extending from the neck, the cystic duct joins...
3.1K
01:29Chronic Pancreatitis II: Collaborative Care
479
The management of chronic pancreatitis is multifaceted, involving a comprehensive approach that includes thorough assessment, diagnostic testing, and a variety of management strategies.
Assessment:
Assessment:
479
01:17Chronic Bowel Disorders: Introduction
904
Chronic bowel diseases are a group of long-term conditions affecting the digestive tract, characterized by inflammation and damage to the gut lining. These conditions primarily include irritable bowel syndrome and inflammatory bowel disease.
Irritable Bowel Syndrome (IBS) is a common disorder affecting the gastrointestinal tract. The distinctive feature is recurrent abdominal pain associated with altered bowel movements, manifesting as constipation, diarrhea, or fluctuating between both. The...
Irritable Bowel Syndrome (IBS) is a common disorder affecting the gastrointestinal tract. The distinctive feature is recurrent abdominal pain associated with altered bowel movements, manifesting as constipation, diarrhea, or fluctuating between both. The...
904
01:22Appendicitis-I: Introduction
3.5K
The appendix, a small, narrow, blind tube extending from the inferior part of the cecum, is widely regarded as a vestigial organ, having lost much of its original function through evolution. Despite its diminished role, the appendix can become inflamed, a condition known as appendicitis.
Etiology: Appendicitis can arise from various causes, primarily rooted in the obstruction of the appendix lumen. Factors contributing to this obstruction include fecal accumulation, lymphoid hyperplasia and, in...
Etiology: Appendicitis can arise from various causes, primarily rooted in the obstruction of the appendix lumen. Factors contributing to this obstruction include fecal accumulation, lymphoid hyperplasia and, in...
3.5K