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Updated: Mar 28, 2026

Occlusion of the Great and Small Saphenous Vein Using Copolymeric Glue Based on N-Butyl Cyanoacrylate and Methacryloxy Sulfolane
Published on: December 9, 2022
[Postoperative relapses of varicose disease]
A V Pokrovski1, I M Ignat'ev2, R A Bredikhin2
1Institute of Surgery named after A.V. Vishnevsky under the RF Ministry of Public Health, Moscow, Russia; Russian Medical Academy of Postgraduate Education, Moscow, Russia.
Abstract:
Analysed herein are the results of examining and treating a total of 290 patients presenting with relapses of varicose disease, including 198 women and 92 men. The patients' age averaged 51.6 ± 8.7 years, with the mean term of the appearance of relapses after surgery amounting to 4.8 ± 1.4 years and that of reoperation - 11.1 ± 7.5 years. According to the CEAP classification, the patients were subdivided as follows: C2 - 36 (12.4 %), С3 - 117 (40.4 %), С4 - 103 (35.5 %), С5 - 20 (6.9 %), С6 - 14 (4.8 %). All patients underwent ultrasound duplex scanning. Relapses in the basin of the great saphenous vein were revealed in 205 (70.63 %) patients, in the basin of the small saphenous vein in 65 (22.4 %) subjects. Neoangiogenesis was observed in 62 (21.3 %) cases, pathological reflux from pelvic veins as a cause of relapses - in 31 (10.7 %) patients, varicosity-altered tributaries of the great and small saphenous veins, not connected with the pathological stump or unremoved trunk - in 52 (17.9 %) cases. Based on the results of diagnosis, treatment was carried out in 241 patients. 179 patients underwent various types of interventions, of these, 94 with the use of minimally invasive therapeutic technologies. 76 patients were subjected to different methods of phlebosclerosing treatment, of these 62 in outpatient conditions. The study showed negative influence of axial reflux along through deep veins on the appearance and course of varicose veins relapses. The remote results of treatment at terms from one year to 9 years (mean 4.9 ± 2.6 years) were studied in 76 patients. Good results were noted in 52 (68.5 %) patients, satisfactory outcomes were observed in 22 (28.9 %), and unsatisfactory results - in 2 (2.6 %) patients.
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