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Epidemiology of Frontotemporal Lobar Degeneration in Northern Finland
Laura Luukkainen1, Risto Bloigu2, Virpi Moilanen3
1Department of Neurology, Institute of Clinical Medicine, University of Oulu, Oulu, Finland ; Department of Neurology, Oulu University Hospital, Oulu, Finland.
Background:
Frontotemporal lobar degeneration (FTLD) is responsible for as many as every fifth case of early-onset dementia. Very few epidemiological studies of FTLD have been conducted; there are no published epidemiological data of FTLD from Finland or the other Nordic countries. The C9ORF72 expansion-associated FTLD is common in Finland; thus, the prevalence of FTLD is expected to be high in this population.
Methods:
We retrospectively evaluated the incidence and prevalence of FTLD in university hospital settings in Northern Finland.
Results:
The mean 1-year incidence of FTLD was 5.54/100,000 (range 1.9-11.3/100,000) in the population aged 45-65 years. The prevalence of FTLD in the same age group was 20.5/100,000.
Conclusion:
The incidence and prevalence of FTLD in Finland seem to be the highest in Europe. However, studies from different countries may not be directly mutually comparable due to methodological issues.
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