Related Experiment Video
Updated: Mar 28, 2026
10:42
A Postoperative Evaluation Guideline for Computer-Assisted Reconstruction of the Mandible
Published on: January 28, 2020
7.2K
[Reconstruction of Defects after Oncologic Resection and Radiation - Indications for Microsurgical Reconstruction]
T Kremer1, T Cordts1, C Hirche1
1BG Unfallklinik Ludwigshafen und Ruprecht-Karls-Universität Heidelberg, Klinik für Hand, Plastische und Rekonstruktive Chirurgie, Schwerbrandverletztenzentrum, Klinik für Plastische Chirurgie, Ludwigshafen.
Handchirurgie, Mikrochirurgie, Plastische Chirurgie : Organ Der Deutschsprachigen Arbeitsgemeinschaft Fur Handchirurgie : Organ Der Deutschsprachigen Arbeitsgemeinschaft Fur Mikrochirurgie Der Peripheren Nerven Und Gefasse : Organ Der V
|December 18, 2015
Summary
Radiation therapy for extremity soft tissue sarcomas can cause complications like poor wound healing and tissue death. Advanced plastic surgery techniques, particularly free tissue transfer, are often necessary to manage this radiation-induced morbidity.
Area of Science:
- Oncology
- Plastic Surgery
- Radiation Oncology
Background:
- Soft tissue sarcomas in extremities often require radiation therapy for tumor control.
- Adjuvant and neoadjuvant radiation increase morbidity, including impaired wound healing, ulcers, and osteonecrosis.
- Pathological changes include altered cell mediators, fibrosis, reduced cell division, and diminished vascularity.
Purpose of the Study:
- To review local conservative treatment options for radiation-induced morbidity.
- To describe plastic surgical reconstructive techniques for managing radiation-induced local morbidity.
- To highlight the role of advanced reconstructive methods in treating complications from radiation therapy.
Main Methods:
- Review of conservative local treatment modalities.
- Description of various plastic surgical reconstructive techniques.
- Evaluation of complication rates associated with different surgical approaches.
Main Results:
- Conservative treatments show limited success rates.
- Less complex reconstructive options like random pattern flaps and split-thickness skin grafts are frequently associated with complications.
- Free tissue transfer is often required for successful reconstruction in complex cases.
Conclusions:
- Radiation therapy for extremity soft tissue sarcomas leads to significant local morbidity.
- Plastic surgical interventions are crucial for managing these complications.
- Free tissue transfer represents a vital reconstructive option for complex radiation-induced tissue defects.
