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Updated: Mar 28, 2026

Efficient Synthesis of Polyfunctionalized Benzenes in Water via Persulfate-promoted Benzannulation of α,β-Unsaturated Compounds and Alkynes
Published on: December 16, 2019
Generation of thioethers via direct C-H functionalization with sodium benzenesulfinate as a sulfur source
Yingcai Ding1, Wei Wu, Wannian Zhao
1Pharmacy School, Jiangsu University, Xuefu Road 301, Zhenjiang, 212013, People's Republic of China. ahz@ujs.edn.cn.
Abstract:
A novel ammonium iodide-induced sulfenylation method of flavones, indole and arylimidazo[1,2-a]pyridines using stable and odorless sodium benzenesulfinates as sulfur sources was developed, generating regioselective derivatives in good yields. This method has enriched current thioether-producing methods and provided a good example of using ammonium iodide as a reaction inducer instead of iodine to make thioethers under environmentally friendly and odorless conditions.
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