Exogenous Ochronosis
Prachi A Bhattar1, Vijay P Zawar2, Kiran V Godse1
1Department of Dermatology, Dr. D. Y. Patil Hospital and Research Institute, Nerul, Navi Mumbai, India.
Indian Journal of Dermatology
|December 18, 2015
Summary
Exogenous ochronosis (EO) is a rare skin condition causing blue-black pigmentation, often from skin-lightening products. Treatment options for this disfiguring disorder are currently limited and disappointing.
Area of Science:
- Dermatology
- Cutaneous Medicine
Background:
- Exogenous ochronosis (EO) presents as blue-black skin pigmentation.
- It is a complication of long-term hydroquinone use, but also phenol, resorcinol, or quinine.
- EO is clinically and histologically similar to endogenous ochronosis (alkaptonuria).
Purpose of the Study:
- To summarize the characteristics and challenges of exogenous ochronosis.
- To highlight diagnostic methods and treatment difficulties.
Main Methods:
- Review of clinical and histological features of exogenous ochronosis.
- Discussion of diagnostic tools like dermoscopy and confocal microscopy.
- Assessment of current treatment limitations.
Main Results:
- Exogenous ochronosis is characterized by specific pigmentation patterns.
- Non-invasive diagnostic tools aid in identifying the condition.
- Effective treatment strategies for exogenous ochronosis remain elusive.
Conclusions:
- Exogenous ochronosis is a challenging cosmetic disorder with limited therapeutic options.
- Further research is needed to develop effective treatments for exogenous ochronosis.
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