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Chronic Spontaneous Urticaria: A Questionnaire Survey.
Natasha Gattey1, Bahar Bahrani1, Peter R Hull2
1Division of Dermatology, University of Saskatchewan, Saskatoon, Saskatchewan, Canada.
Journal of Cutaneous Medicine and Surgery
|December 19, 2015
Summary
Chronic spontaneous urticaria (CSU) significantly impacts lifestyle, often persisting for decades. This condition, frequently linked to autoimmune diseases, causes significant disability and frustration due to ineffective treatments.
Area of Science:
- Dermatology
- Immunology
- Clinical Medicine
Background:
- Chronic spontaneous urticaria (CSU) defined as urticaria >6 weeks without identifiable cause.
- CSU is associated with significant patient disability and reduced quality of life.
Purpose of the Study:
- To survey patients with CSU to establish prognosis.
- To evaluate the efficacy of treatments for CSU.
- To investigate suspected causality and lifestyle effects of CSU.
Main Methods:
- Survey of 101 patients diagnosed with CSU between 2003 and 2013.
- Data collected via questionnaire from participating patients.
Main Results:
- Mean age of onset 36 years; average symptom duration 8.8 years.
- 7% had autoimmune thyroiditis; 17% had other autoimmune diseases.
- Pruritus, disturbed sleep, anxiety were common; >70% missed work/school; treatment efficacy was frustratingly low.
Conclusions:
- CSU frequently co-occurs with autoimmune diseases.
- CSU can persist for decades, causing substantial lifestyle disruption.
- Patient-reported outcomes highlight significant unmet needs in CSU management.
