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Updated: Mar 28, 2026
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Genome-wide Gene Deletions in Streptococcus sanguinis by High Throughput PCR
Published on: November 23, 2012
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Complete Genome Sequence of Streptococcus anginosus J4211, a Clinical Isolate
Maliha Rahman1, Scott V Nguyen1, Kimberly A McCullor1
1Department of Pharmaceutical Sciences, The University of Oklahoma College of Pharmacy, Oklahoma City, Oklahoma, USA.
Genome Announcements
|December 19, 2015
Summary
Streptococcus anginosus, a pathogen causing abscesses, has had its complete genome sequenced. This analysis reveals the presence of two prophages and several mobile genetic elements within the J4211 strain.
Area of Science:
- Microbiology
- Genomics
- Pathogen Research
Background:
- Streptococcus anginosus is an opportunistic human pathogen.
- This bacterium is known to cause abscesses in various organs, including the brain and liver.
Purpose of the Study:
- To announce the complete genome sequence of a clinically isolated strain of Streptococcus anginosus.
- To provide a genomic resource for understanding S. anginosus pathogenesis.
Main Methods:
- Whole-genome sequencing of the clinical isolate S. anginosus J4211.
- Bioinformatic analysis to identify genomic features.
Main Results:
- The complete genome sequence of S. anginosus J4211 was successfully obtained.
- The genome harbors two integrated prophages.
- Multiple mobile genetic elements were identified within the genome.
Conclusions:
- The genome sequence provides a valuable resource for future research into S. anginosus.
- Understanding the genomic content, including prophages and mobile elements, may offer insights into the bacterium's virulence and evolution.
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