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[Diagnostic accuracy of malignancy risk index II in post-menopausal women with adnexal tumours]
Joaquín Darío Treviño-Báez1, Javier Alejandro Cantú-Cruz2, Javier Medina-Mercado3
1Servicio de Neonatología, Unidad Médica de Alta Especialidad N.° 23, «Dr. Ignacio Morones Prieto», Monterrey, Nuevo León, México.
Background:
The purpose of the diagnostic evaluation of adnexal tumours is to exclude the possibility of malignancy. The malignancy risk index II identifies patients at high risk for ovarian cancer. The cut-off value is greater than 200.
Objective:
To evaluate the diagnostic accuracy of malignancy risk index II in post-menopausal women with adnexal tumours in relation to the histopathological results.
Material And Methods:
A total of 138 women with an adnexal mass were studied. The malignancy risk index II was determined in all of them. They were divided into two groups according to the histopathology results; 69 patients with benign tumours and 69 patients with malignant tumours. A diagnostic test type analysis was performed with respect to the results of malignancy risk index II ≤ 200 or greater than this.
Results:
The percentages and 95% confidence intervals were calculated. The accuracy was 81.8% (75.5-88.3), sensitivity 76.8% (66.9-86.7), specificity 87% (79.1-94.9), with a positive predictive value of 85.5% (76.7-94.3), and a negative predictive value of 78.9% (69.7-88.1). The positive likelihood ratio was 590, and the negative likelihood ratio was 0.266.
Conclusions:
The malignancy risk index II has good performance in the proper classification of post-menopausal women with adnexal masses, both benign and malignant, with an accuracy of 81.8%.
