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Maternal Height and Infant Body Mass Index Are Possible Risk Factors for Developmental Dysplasia of the Hip in Female
Hakan Atalar1, Cuneyd Gunay, Osman Yuksel Yavuz
1Departments of Orthopaedics and Traumatology, Gazi University School of Medicine, Ankara 06500, Turkey.
Insights
Short maternal height and a low maternal height to infant BMI ratio are significant risk factors for developmental dysplasia of the hip (DDH). These findings highlight potential new indicators for identifying infants at risk of DDH.
Area of Science:
- Orthopedics
- Pediatrics
- Genetics
Background:
- Developmental dysplasia of the hip (DDH) is a common condition with complex causes.
- The exact etiology of DDH remains unclear despite its prevalence.
Purpose of the Study:
- To identify novel risk factors for DDH.
- To evaluate maternal and infant anthropometric measurements as potential predictors of DDH.
Main Methods:
- A case-control study involving 71 female first-born infants (28 with DDH, 43 healthy).
- Maternal pre-pregnancy height/weight and infant birth height/weight/BMI were recorded.
- Ratios between maternal and infant parameters were calculated.
Main Results:
- Short maternal height was significantly associated with DDH.
- A low maternal height to infant BMI ratio (MH/I-BMI) was also a significant risk factor for DDH.
Conclusions:
- Maternal stature and the MH/I-BMI ratio may serve as important indicators for DDH risk.
- Further research with larger cohorts is needed to validate these findings.
Abstract:
Developmental dysplasia of the hip (DDH) is a wide-spectrum disease with a multifactorial etiology and, despite its prevalence, no definitive etiology has yet been established. The aim of this study was to investigate new risk factors for DDH by evaluating newly defined potential risk factors. A total of 71 infants were separated into 2 groups:Group I, 28 female first-born infants diagnosed with DDH and their mothers;and Group II, 43 healthy female first-born infants and their mothers. The maternal height and weight before pregnancy, infant height and weight at birth, and body mass index (BMI) of both mother and infant were determined. Calculations were made of the ratios between these parameters. Of the examined risk factors, only maternal height and the ratio of maternal height to infant BMI (MH/I-BMI) were found to be significant for DDH in infants. In conclusion, the results of this study show that a short maternal height and a low MH/I-BMI increase the risk of DDH. Further studies with a larger series are necessary to confirm these results.
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