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When a pathogen enters the body and reproduces, it can cause an infection, damage body cells, and cause illness symptoms that eventually lead to disease. Therefore, its prevention requires breaking the chain of infection.
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Author Spotlight: Advancing Syphilis Research — Innovations in Treponema pallidum Cultivation and Genetic Engineering
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Syphilis: Is it making resurgence?

Bela J Shah1, Darshan R Karia1, Chirag L Pawara1

  • 1Department of Skin and VD, B.J. Medical College and Civil Hospital, Ahmedabad, Gujarat, India.

Indian Journal of Sexually Transmitted Diseases and AIDS
|December 23, 2015
PubMed
Summary
This summary is machine-generated.

Syphilis incidence is rising, with HIV infection and homosexual behavior as key risk factors. This study analyzed recent syphilis trends in patients attending an STI clinic.

Keywords:
Acquired syphilishuman immunodeficiency virusresurgencesexually transmitted infections

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Area of Science:

  • Infectious Diseases
  • Public Health
  • Epidemiology

Background:

  • Syphilis, a complex sexually transmitted infection (STI), presents with diverse manifestations mimicking other diseases.
  • Despite the rise in viral STIs, syphilis remains a significant public health concern.
  • Understanding syphilis trends is crucial for effective STI control strategies.

Purpose of the Study:

  • To investigate the recent epidemiological trends of acquired syphilis.
  • To analyze the demographic and clinical characteristics of syphilis patients.
  • To identify risk factors associated with syphilis infection in an STI clinic setting.

Main Methods:

  • Retrospective analysis of syphilis cases registered between January 2013 and December 2014.
  • Inclusion of sociodemographic, clinical, and investigational data.
  • Comparison of current incidence with data from the preceding four years.

Main Results:

  • Syphilis was diagnosed in 110 out of 1010 STI patients (10.9%).
  • Males constituted 70.9% of cases, with 22.7% being men who have sex with men (MSM).
  • Primary, secondary, and latent syphilis were diagnosed in 25.5%, 42.7%, and 31.8% of cases, respectively. Lymphadenopathy was observed in 50% of patients. Mixed infections, notably with genital herpes, occurred in 26.4%, and 24.5% were HIV-reactive.

Conclusions:

  • The incidence of syphilis shows an increasing trend.
  • HIV infection and homosexual behavior are identified as major risk factors.
  • These findings highlight the need for targeted interventions and continued surveillance for syphilis.