Normal Macular Thickness in Healthy Indian Eyes Using Spectral Domain Optical Coherence Tomography
Tanie Natung1, Avonuo Keditsu, Laura Amanda Lyngdoh
1From the *Department of Ophthalmology, North Eastern Indira Gandhi Regional Institute of Health & Medical Sciences (NEIGRIHMS), Meghalaya, India; and †Department of Ophthalmology, Sarojini Naidu Medical College, Agra, India.
Purpose:
To determine macular thickness and its variation with age and sex in healthy Indian eyes using Zeiss spectral domain optical coherence tomography (SD-OCT).
Design:
A prospective, cross-sectional study.
Methods:
Four hundred healthy adult subjects (≥18 years) underwent macular cube scanning using Zeiss SD-OCT. Macular thickness from all 9 regions of the Early Treatment Diabetic Retinopathy Study map was documented for each subject. Variations in macular thickness by age and sex were determined.
Results:
The mean age of the subjects was 38.05 ± 12.13 (range, 18-78) years. The mean ages in men and women were 39.19 ± 12.16 and 37.13 ± 12.05 years, respectively (P > 0.05). The mean central subfield thickness (CST) of all subjects was 240.40 ± 18.26 μm, and mean macular thickness was 287.87 ± 18.07 μm. The mean CST in the right and left eyes were 240.40 ± 18.25 μm and 239.65 ± 17.73 μm, respectively (P = 0.55). Males were associated with greater mean CST and mean macular thickness compared with females (P < 0.05). There was an association of mean CST with sex (adjusted r = 0.095; P < 0.05) but not with age. Overall, the nasal quadrant was the thickest followed by the superior, inferior, and temporal subfields.
Conclusions:
This is the normative data for macular thickness in healthy Indian eyes using Zeiss SD-OCT. This will serve as a baseline for diagnosing and treating macular pathologies in Indian eyes because such data using Zeiss SD-OCT in Indian eyes have previously been lacking.
