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Related Experiment Video

Updated: Mar 28, 2026

A Preclinical Model of Exertional Heat Stroke in Mice

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Recurrent Heat Stroke in a Runner: Race Simulation Testing for Return to Activity.

William O Roberts¹, Jason C Dorman, Michael F Bergeron

¹1Department of Family Medicine and Community Health, University of Minnesota, Minneapolis, MN; 2Sanford Sports Science Institute, Sanford Health, Sioux Falls, SD; 3Youth Sports of the Americas, Birmingham, AL; 4Lemak Health, Birmingham, AL.

Medicine and Science in Sports and Exercise

|December 24, 2015

Summary

A recreational runner experienced exertional heat stroke (EHS) twice. Race simulation testing identified EHS risk, guiding recommendations for safe return to running and heat acclimatization.

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Area of Science:

Sports Medicine
Environmental Physiology
Exercise Science

Background:

Exertional heat stroke (EHS) is a critical condition affecting endurance athletes.
Recurrent EHS episodes pose significant risks for athletes.
Understanding individual risk factors is crucial for safe athletic participation.

Observation:

A 30-year-old male recreational runner collapsed with EHS in two half marathons within six weeks.
Despite normal heat tolerance tests, a race simulation revealed a high risk for EHS at elevated temperatures.
Significant body weight loss and sweat/sodium loss were noted during the simulation.

Findings:

The runner experienced EHS despite seemingly normal heat tolerance.
Race simulation testing identified a critical threshold for EHS development.
Physiological responses during simulation indicated significant dehydration and electrolyte loss.

Implications:

Recurrent EHS necessitates careful evaluation, including race simulation testing.
Recommendations for athletes with EHS include limiting run duration, fluid/electrolyte replacement, heat acclimatization, and recognizing early symptoms.
Race simulation can aid in developing personalized return-to-activity protocols for athletes with recurrent EHS.