Related Experiment Video
Updated: Mar 28, 2026

Methods for Quantitative Detection of Antibody-induced Complement Activation on Red Blood Cells
Published on: January 29, 2014
Autoimmune Hemolysis: A Journey through Time
1Professor Emeritus, Medicine and Laboratory Medicine and Pathobiology, University of Toronto, St Michael's Hospital, Toronto, ON, Canada.
Abstract:
The existence of autoimmune diseases in humans has been known for almost 100 years. Currently, autoimmune pathogenesis has been attributed to more than 40 human diseases; yet it is still not clear what immune abnormalities conclusively prove underlying autoimmune pathogenesis. Hence, although much has been learned, research is still needed for complete elucidation of the mechanisms of the immune dysregulation in AIHA. Better understanding of the underlying mechanism(s) may allow for development of more specific therapies of these not uncommon and often difficult-to-treat disorders.
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