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A Systems Approach to Understand Antigen Presentation and the Immune Response

Nadine L Dudek1, Nathan P Croft1, Ralf B Schittenhelm1

  • 1Department of Biochemistry and Molecular Biology, School of Biomedical Sciences, Monash University, Clayton, VIC, 3800, Australia.

Methods in Molecular Biology (Clifton, N.J.)
|December 25, 2015
PubMed
Summary

The mammalian immune system uses innate and adaptive responses to detect threats. Combining proteomics with peptide antigen identification offers a holistic view of immune system function.

Keywords:
Antigen presentationHuman leukocyte antigensMajor histocompatibility complexMass spectrometryPeptide ligands

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