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Repeatability and reproducibility of ocular biometry using a new noncontact optical low-coherence interferometer
Jinhai Huang1, Giacomo Savini1, Fan Wu1
1From the School of Ophthalmology and Optometry and Eye Hospital (Huang, Wu, X. Yu, Yang, A. Yu, Y. Yu, Wang), Wenzhou Medical University, Wenzhou, and the Key Laboratory of Vision Science (Huang, Yang, A. Yu, Y. Yu, Wang), Ministry of Health, P.R. China, Wenzhou, Zhejiang, China; the G.B. Bietti Foundation IRCCS (Savini), Rome, Italy.
This study evaluated a new optical biometer for eye measurements. It found excellent precision for axial length, anterior chamber depth, and keratometry in both healthy eyes and those with cataracts, though white-to-white measurements were less precise in cataract patients.
Area of Science:
- Ophthalmology
- Medical Devices
- Biometry
Background:
- Accurate ocular biometry is crucial for refractive surgery and intraocular lens calculations.
- New devices are continuously developed to improve measurement precision and efficiency.
Purpose of the Study:
- To evaluate the precision of a novel noncontact optical low-coherence interferometer (Aladdin) for ocular biometry.
- To assess its performance in both healthy subjects and patients with cataracts.
Main Methods:
- An observational, cross-sectional study was conducted involving 98 participants (52 healthy eyes, 46 cataract eyes).
- Ocular parameters including axial length (AL), anterior chamber depth (ACD), keratometry (K), and white-to-white (WTW) distance were measured using the Aladdin biometer by two operators.
- Intraoperator repeatability and interoperator reproducibility were assessed using test-retest reliability, coefficient of variation (CoV), and intraclass correlation coefficient (ICC), alongside Bland-Altman analysis.
Main Results:
- The Aladdin biometer demonstrated high intraoperator repeatability and interoperator reproducibility for AL, ACD, and K measurements in both healthy subjects and cataract patients.
- Measurements of AL were the most repeatable and reproducible parameter across both groups.
- While WTW measurements showed high precision in healthy eyes, they exhibited lower repeatability and reproducibility in patients with cataracts.
Conclusions:
- The Aladdin noncontact optical low-coherence interferometer provides excellent precision for measuring AL, ACD, and K values in both healthy eyes and eyes with cataracts.
- The precision of WTW measurements may be reduced in patients with cataracts, warranting careful consideration.
