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Blastomycosis.

W D Steck1

  • 1Department of Dermatology, Cleveland Clinic Foundation, Ohio.

Dermatologic Clinics
|April 1, 1989
PubMed
Summary
This summary is machine-generated.

Blastomycosis, a fungal infection, can be fatal but may resolve on its own. While amphotericin B is the primary treatment, imidazole drugs like ketoconazole show promise for treating this rare disease.

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Area of Science:

  • Mycology
  • Infectious Diseases
  • Medical Mycology

Background:

  • Blastomycosis is an uncommon infectious disease.
  • It is caused by the fungus Blastomyces dermatitidis.
  • The disease course can range from self-healing to fatal.

Purpose of the Study:

  • To review the treatment options for blastomycosis.
  • To highlight the efficacy of imidazole drugs in blastomycosis treatment.

Main Methods:

  • Literature review of antifungal treatments.
  • Analysis of clinical data on blastomycosis therapy.

Main Results:

  • Amphotericin B remains the established drug of choice for blastomycosis.
  • Imidazole antifungals, including ketoconazole, miconazole, itraconazole, and econazole, demonstrate therapeutic potential.

Conclusions:

  • Imidazole drugs represent a promising alternative or adjunctive therapy for blastomycosis.
  • Further research may solidify the role of these antifungals in clinical practice.