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Published on: September 12, 2019
Angiosarcoma of the Vulva: A Case Report.
Michal Sheinis1, Matthew Cesari, Amanda Selk
11Faculty of Medicine, University of Toronto, Toronto, Ontario, Canada; 2Department of Anatomic Pathology, Sunnybrook Health Sciences Centre, Toronto, Ontario, Canada; 3Department of Laboratory Medicine and Pathobiology, University of Toronto, Toronto, Ontario, Canada; 4Department of Gynecology, Women's College Hospital, Toronto, Ontario, Canada; and 5Department of Obstetrics and Gynecology, University of Toronto, Toronto, Ontario, Canada.
A seemingly harmless vulvar lesion may hide aggressive cancer. Biopsy is crucial for any painful, growing, or changing vulvar lesion to rule out malignancy.
Area of Science:
- Gynecologic Oncology
- Dermatopathology
Background:
- Vulvar lesions present a diagnostic challenge, with varied etiologies ranging from benign conditions to malignancies.
- Early detection of vulvar cancer is critical for improving patient outcomes.
Observation:
- This case highlights a vulvar lesion that appeared benign but was histopathologically confirmed as an aggressive cancer.
- The patient's lesion exhibited concerning clinical features, prompting further investigation.
Findings:
- Histopathological examination revealed an aggressive malignancy despite the lesion's benign clinical appearance.
- The case underscores the importance of thorough diagnostic evaluation for all vulvar lesions.
Implications:
- Vulvar lesion biopsy is essential for accurate diagnosis, especially when symptoms like pain, rapid growth, or altered morphology are present.
- Clinicians should maintain a high index of suspicion for malignancy in evaluating vulvar lesions, irrespective of initial appearance.

