Related Experiment Video
Updated: May 29, 2025

Investigating Intestinal Inflammation in DSS-induced Model of IBD
Published on: February 1, 2012
Associations with sexual dysfunction among a Canadian cohort with inflammatory bowel disease
Adam V Weizman1, Derek M Nguyen1, Laura E Targownik1
1Division of Gastroenterology, Department of Medicine, Mount Sinai Hospital, University of Toronto, Toronto, Ontario, M5G 1X5, Canada.
Sexual dysfunction significantly affects individuals with inflammatory bowel disease (IBD). Depression is a key factor, highlighting the need for integrated care to manage sexual health in IBD patients.
Area of Science:
- Gastroenterology
- Sexual Medicine
- Psychiatry
Background:
- Inflammatory bowel disease (IBD) frequently impacts patients' quality of life.
- Sexual dysfunction is a prevalent yet often overlooked complication in IBD management.
- Understanding the scope and contributing factors of sexual dysfunction in IBD is crucial.
Purpose of the Study:
- To characterize the prevalence and severity of sexual dysfunction in a Canadian IBD patient cohort.
- To identify factors associated with sexual dysfunction among IBD patients, stratified by sex.
- To inform clinical practice regarding sexual health in IBD.
Main Methods:
- A cross-sectional survey design was employed.
- The Female Sexual Dysfunction Scale (FSDS) and Male Sexual Dysfunction Scale (MSDS) were used for assessment.
- Multiple linear regression analyses were performed to identify associated factors.
Main Results:
- 351 IBD patients completed the survey.
- Sexual dysfunction was reported by both females (IBD-FSDS 14.1) and males (IBD-MSDS 7.2).
- Depression showed a strong association with sexual dysfunction in both sexes (β=0.92 for men, β=0.84 for women, P<.001).
Conclusions:
- Sexual dysfunction is common in IBD patients, with a greater impact observed in women.
- Depression is a significant correlate of sexual dysfunction in this population.
- Multidisciplinary care is essential for addressing sexual health concerns in individuals with IBD.
Related Concept Videos
Inflammatory Bowel Disease III: Diagnostic Studies and Management I-Nutritional Therapy
Diagnostic studies
A colonoscopy is the definitive screening test, distinguishing ulcerative colitis from other colon diseases with similar symptoms. During a colonoscopy test, inflamed mucosa with exudate ulcerations can be observed, and biopsies are taken to determine the histologic characteristics of the...
Chronic Bowel Disorders: Introduction
Irritable Bowel Syndrome (IBS) is a common disorder affecting the gastrointestinal tract. The distinctive feature is recurrent abdominal pain associated with altered bowel movements, manifesting as constipation, diarrhea, or fluctuating between both. The...
Inflammatory Bowel Disease I: Ulcerative Colitis
Inflammatory bowel disease, or IBD, encompasses a group of disorders characterized by chronic inflammation or ulceration of the gastrointestinal tract.
Risk Factors
The exact cause of IBD remains unclear, although it is believed to be due to a mix of genetic, environmental, microbial, and immune factors. Genetic factors are significant in determining susceptibility to IBD, with family history being a critical risk factor. Individuals with a first-degree relative who has IBD are at...
Inflammatory Bowel Disease II: Crohn's Disease
Inflammatory bowel disease, commonly known as IBD, refers to a collection of disorders that lead to persistent inflammation of the gastrointestinal tract. The two types of IBD are ulcerative colitis, which impacts the colon, and Crohn's disease, which can involve any part of the gastrointestinal segment.
Crohn's disease
Crohn's disease is a chronic, systemic inflammatory bowel disease (IBD) that predominantly affects the gastrointestinal tract. It is marked by...
Irritable Bowel Syndrome II: Clinical Features and Diagnostic Evaluation
Irritable Bowel Syndrome (IBS) is classified into subtypes based on the predominant bowel habits as determined by the Bristol Stool Form Scale (BSFS). The subtypes are:
Inflammatory Bowel Disease IV: Pharmacological Management
Pharmacologic...

