Related Experiment Video
Updated: Mar 28, 2026

Endoscopic Endonasal Trans-sphenoidal Approach: Minimally Invasive Surgery for Pituitary Adenomas
Published on: January 17, 2018
Managing acute invasive fungal sinusitis.
Kristina M Dwyhalo1, Carrlene Donald, Anthony Mendez
1At the Mayo Clinic Arizona in Phoenix, Ariz., Kristina M. Dwyhalo and Carrlene Donald practice in the Department of Otolaryngology/Head & Neck Surgery, Anthony Mendez is an instructor in the Mayo Clinic College of Medicine and associate program director of the ENT PA fellowship in the Department of Otolaryngology/Head & Neck Surgery, and Joseph Hoxworth is a neuroradiologist. The authors have disclosed no potential conflicts of interest, financial or otherwise.
Acute invasive fungal sinusitis is a life-threatening condition, particularly in immunocompromised individuals. Prompt medical attention, including hospital admission for antifungal treatment and surgery, is vital for survival.
Area of Science:
- Otolaryngology
- Infectious Diseases
- Mycology
Background:
- Acute invasive fungal sinusitis is a severe and potentially fatal fungal infection.
- Immunocompromised patients are at higher risk for severe outcomes.
Purpose of the Study:
- To emphasize the critical need for early diagnosis and intervention in acute invasive fungal sinusitis.
- To highlight the role of primary care providers in identifying this condition.
Main Methods:
- This is a review and expert opinion piece, not a primary research study.
- Discussion focuses on clinical presentation, risk factors, and management strategies.
Main Results:
- Early recognition and prompt treatment significantly improve patient outcomes.
- High index of suspicion is necessary for timely diagnosis.
Conclusions:
- Acute invasive fungal sinusitis requires urgent medical and surgical management.
- Intravenous antifungal therapy and surgical debridement are key treatment modalities.
- Primary care providers play a crucial role in the initial detection and referral of these patients.
Related Concept Videos
Epistaxis
Etiology
Possible causes of this condition include high blood pressure, trauma, low humidity, upper respiratory tract infections, allergies, foreign bodies, nasal inhalation of corticosteroids or illicit drugs, excessive use of decongestant nasal sprays, facial or nasal surgery, anatomic malformation, tumors, or systemic...
Drugs Used in Upper Respiratory Disorders: Overview
Antihistamines (e.g., Benadryl) block histamines from binding. Histamines are chemicals released during an allergic reaction in the body. As a...
Acute Respiratory Failure-V
Ensure that patients are monitored continuously for their response to therapy, including changes in...
Tonsillitis II: Management
Acute Pharyngitis
Acute pharyngitis is the inflammation of the back of the throat (pharynx), commonly resulting in a sore throat. It is a frequently encountered condition that prompts individuals to seek medical advice.
Classification
Acute pharyngitis can be categorized based on its underlying cause:
Pneumonia IV: Management
Bacterial Pneumonia Treatment
For bacterial pneumonia, antibiotics serve as the cornerstone of therapy. Initial treatment often begins with empirical antibiotics, tailored to the anticipated causative organism and adjusted based on culture results. Key antibiotic choices include:

