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Related Experiment Video

Updated: Mar 28, 2026

Micro-particle Image Velocimetry for Velocity Profile Measurements of Micro Blood Flows

Published on: April 25, 2013

Numerical methods for simulating blood flow at macro, micro, and multi scales.

Yohsuke Imai¹, Toshihiro Omori¹, Yuji Shimogonya²

¹School of Engineering, Tohoku University, Sendai, Japan.

Journal of Biomechanics

|December 26, 2015

Summary

Computational biomechanics of blood flow utilizes advanced numerical methods and computational meshes for cellular to organ-scale simulations. This review focuses on mesh types and multi-scale modeling advancements in blood flow research.

Keywords:

Computational fluid dynamics Hemodynamics Red blood cell

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Area of Science:

Computational fluid dynamics
Biomedical engineering
Hemodynamics

Background:

Numerical methods for blood flow simulation have advanced significantly over the past decade.
Applications range from cellular to organ scales.
Computational mesh type is a key characteristic differentiating numerical methods.

Purpose of the Study:

Provide an overview of recent numerical methods for blood flow simulation.
Focus on the role of computational meshes in these methods.
Discuss progress in multi-scale modeling of blood flow.

Main Methods:

Classification of numerical methods based on computational mesh: fixed mesh, moving mesh (boundary-fitted), and mesh-free.
Review of methods applied to macro and micro-scale blood flow simulations.
Exploration of multi-scale modeling techniques.

Main Results:

Numerical methods, categorized by mesh type, offer diverse capabilities for blood flow analysis.
Advancements in mesh strategies enhance simulation accuracy and applicability.
Multi-scale modeling is crucial for comprehensive understanding of blood flow dynamics.

Conclusions:

The choice of computational mesh significantly impacts the performance and application of blood flow simulation methods.
Continued development in numerical techniques and multi-scale modeling is essential for advancing computational biomechanics.
Future research should leverage these methods for deeper insights into physiological and pathological blood flow.